2-Chloromethyl-6-nitro-benzooxazole - Names and Identifiers
2-Chloromethyl-6-nitro-benzooxazole - Physico-chemical Properties
Molecular Formula | C8H5ClN2O3
|
Molar Mass | 212.59 |
Melting Point | 69-70°C |
Storage Condition | Room Temprature |
Sensitive | IRRITANT |
MDL | MFCD00775454 |
2-Chloromethyl-6-nitro-benzooxazole - Risk and Safety
2-Chloromethyl-6-nitro-benzooxazole - Introduction
2-(Chloromethyl)-6-nitro-1,3-benzoxazole is an organic compound whose chemical formula is C9H5ClN2O3. The following are some information about the properties, uses, preparation and safety of this compound:
Nature:
1. Appearance: 2-(Chloromethyl)-6-nitro-1,3-benzoxazole is a light yellow to yellow solid.
2. melting point: melting point of 80-82 degrees Celsius.
3. Solubility: It can be dissolved in some organic solvents, such as dimethyl sulfoxide, N,N-dimethylformamide and acetonitrile, but it is difficult to dissolve in water.
Use:
1. 2-(Chloromethyl)-6-nitro-1,3-benzoxazole is commonly used as an intermediate in organic synthesis, for example, it can be used to synthesize other drugs and pesticides.
2. It can also be used as a precursor substance for dyes and color developers.
Preparation Method:
The preparation method of 2-(Chloromethyl)-6-nitro-1,3-benzoxazole can be carried out by the following reactions:
2-amino-4-nitrophenol and chloromethanol are reacted under alkaline conditions to generate 2-(chloromethyl)-4-nitrophenol, which is then subjected to acetic anhydride and alkylation reaction under alkaline conditions to finally obtain the target compound.
Safety Information:
1. 2-(Chloromethyl)-6-nitro-1,3-benzoxazole is an organic compound, which may have potential toxicity and irritation to human body. The specific toxicity data need further study.
2. When handling the compound, good laboratory practices and personal protective measures should be taken, such as wearing protective glasses, gloves and protective clothing.
3. Avoid inhaling the dust or vapor of the compound, avoid skin contact and swallowing.
4. When using and storing the compound, keep away from flammable materials and strong oxidants.
5. The handling and disposal of this compound should comply with local regulations and safe practices.
Last Update:2024-04-09 02:00:56