2-Bromo-3-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - Names and Identifiers
Name | 2-Bromo-3-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
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Synonyms | 2-Bromo-3-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine Pyridine, 2-bromo-3-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
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CAS | 1357387-81-5
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2-Bromo-3-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - Physico-chemical Properties
Molecular Formula | C12H17BBrNO3
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Molar Mass | 313.98 |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD17171339 |
2-Bromo-3-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - Risk and Safety
Hazard Symbols | T - Toxic
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Risk Codes | 25 - Toxic if swallowed
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Safety Description | 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
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Hazard Class | IRRITANT |
2-Bromo-3-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - Introduction
2-Bromo-3-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is an organic compound with the chemical formula C15H21BBrNO2.
Nature:
-Appearance: Colorless to light yellow solid
-melting point: about 93-97 ℃
-Boiling point: about 330 ℃
-Solubility: Soluble in most organic solvents.
Use:
- 2-Bromo-3-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is an important intermediate of organic synthesis, widely used in drug synthesis, pesticide manufacturing, dye synthesis and other fields.
Preparation Method:
The synthesis of 2-Bromo-3-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is mainly obtained by a two-step reaction:
1. In the presence of potassium bromide, 3-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is reacted with bromoethane to give 2-bromo-3-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine;
2.2-bromo-3-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine and ferrous powder are reduced to 2-vinyl -3-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxopyridine -2-) in the presence of acetic acid.
Safety Information:
- 2-Bromo-3-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine has limited toxicity information and should follow chemical safety practices to avoid contact with skin, eyes, and inhalation of gases or smoke.
-Wear protective clothing, gloves, goggles and respiratory protection when handling or handling the compound.
-In storage, should be kept in a dry, ventilated place, away from fire and oxidant.
Last Update:2024-04-09 02:00:56