2-BroMo-3,5-dichloro-4-Methylpyridine - Names and Identifiers
2-BroMo-3,5-dichloro-4-Methylpyridine - Physico-chemical Properties
Molecular Formula | C6H4BrCl2N
|
Molar Mass | 240.91 |
Storage Condition | Inert atmosphere,Room Temperature |
2-BroMo-3,5-dichloro-4-Methylpyridine - Introduction
2-Bromo-3, 5-dichloro-4-methylpyriridine is an organic compound with the chemical formula C6H5BrCl2N. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: It is a colorless to light yellow solid.
-Melting point: about 48-52 degrees Celsius.
-Boiling point: about 244-246 degrees Celsius.
-Density: about 1.85 g/ml.
-Insoluble in water, but soluble in organic solvents such as ethanol and dimethylformamide.
Use:
- 2-Bromo-3, 5-dichloro-4-methylpyriridine can be used in organic synthesis reactions, especially as an intermediate for the synthesis of pesticides and pharmaceutical active molecules.
-It can also be used as a catalyst or catalyst precursor for chemical reactions.
Preparation Method:
2-Bromo-3, 5-dichloro-4-methylpyriridine is generally synthesized by the following steps:
1. Dissolve pyridine in dichloromethane;
2. adding methyl sodium bromide to the reaction solution and reacting with pyridine;
3. Add aluminum trichloride or tin trichloride as a catalyst, and then add a solution of sodium chloride and dichloromethane;
4. finally, hydrogen bromide is added, and the target product is generated by the reaction.
Safety Information:
- 2-Bromo-3, 5-dichloro-4-methylpyriridine contact should avoid skin, eyes and respiratory tract contact, if necessary, wear protective gloves, goggles and respiratory protection equipment.
-It may be harmful to the environment and should be avoided in water, soil and air.
-Observe good laboratory safety practices during storage and handling, and follow relevant regulations and standards.
Last Update:2024-04-09 02:00:45