2-Bromo-5-bromomethylthiazole is an organic compound whose chemical formula is C4H3Br2NOS. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 2-Bromo-5-bromomethylthiazole is a solid that usually appears as white crystals.
-Melting point: Its melting point range is 124-128°C.
-Solubility: 2-bromo-5-bromomethylthiazole can be dissolved in many organic solvents, such as ethanol and dichloromethane.
Use:
-Pesticide: 2-Bromo-5-bromomethylthiazole is commonly used as a raw material for pesticides and fungicides to protect crops from diseases and insect pests.
-Pharmaceutical field: The compound is also used to synthesize certain drugs, such as compounds with antibacterial activity.
Preparation Method:
2-Bromo-5-bromomethylthiazole can be synthesized by the following steps:
1.2-amino -4, 5-dibromothiazole reacts with methyl magnesium bromide to generate an intermediate of 2-bromo -5-bromomethylthiazole.
2. In the presence of a base, the intermediate is subjected to an esterification reaction to obtain the final product.
Safety Information:
-2-Bromo-5-bromomethylthiazole is a toxic compound and direct contact with skin and eyes should be avoided. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
-During operation, attention should be paid to protective measures, such as wearing protective glasses, gloves and protective clothing.
-When storing and handling the compound, follow chemical safety procedures and store it in a cool and dry place, away from fire and oxidizing agents.