2-AMino-3-cyano-4,5- - Names and Identifiers
Name | 2-Amino-3-cyano-4,5-dimethylpyrrole
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Synonyms | AT-51109 2-AMino-3-cyano-4,5- 2-amino-4,5-dimethyl-1H-pyrrol 2-Amino-3-cyano-4,5-dimethylpyrrole 2-AMINO-3-CYANO-4,5-DIMETHYLPYRROLE 2-AMINO-3-CYANO-4,5-DIMETHYL-1H-PYRROLE 2-AMINO-4,5-DIMETHYL-1H-PYRROLE-3-CARBONITRILE 2-Amino-4,5-dimethyl-1H-pyrrole-3-carbonitrile 1H-Pyrrole-3-carbonitrile, 2-amino-4,5-dimethyl-
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CAS | 21392-51-8
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EINECS | 672-210-6 |
InChI | InChI=1/C7H9N3/c1-4-5(2)10-7(9)6(4)3-8/h10H,9H2,1-2H3 |
2-AMino-3-cyano-4,5- - Physico-chemical Properties
Molecular Formula | C7H9N3
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Molar Mass | 135.17 |
Density | 1.17±0.1 g/cm3(Predicted) |
Melting Point | 178-181°C |
Boling Point | 366.2±42.0 °C(Predicted) |
Flash Point | 175.3°C |
Vapor Presure | 1.49E-05mmHg at 25°C |
pKa | 18.46±0.50(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.575 |
2-AMino-3-cyano-4,5- - Risk and Safety
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R41 - Risk of serious damage to eyes
R37/38 - Irritating to respiratory system and skin.
R22 - Harmful if swallowed
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S39 - Wear eye / face protection.
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UN IDs | 3439 |
Hazard Class | IRRITANT |
2-AMino-3-cyano-4,5- - Introduction
2-Amino-3-cyano-4,5-dimethylpyrrole is an organic compound with the molecular formula C7H9N3.
Nature:
-Appearance: Colorless or light yellow solid
-Melting Point: about 160-165 ° C
-Boiling point: about 310 ° C
-Solubility: Soluble in organic solvents such as ethanol, dimethyl sulfoxide
-Main properties: It is an aromatic base, containing amino and cyano functional groups, and has certain activity.
Use:
2-Amino-3-cyano-4,5-dimethylpyrrole is commonly used in organic synthesis as an important intermediate. It can be used in the synthesis of bioactive compounds, fluorescent dyes and photosensitizers.
Method:
2-Amino-3-cyano-4,5-dimethylpyrrole can be prepared by the following methods:
1. Pyrrole reacts with hydrocyanic acid to give a pyrrole-3-aldehyde compound, which then reacts with carbamate to give a 2-amino -3-methyl pyrrole-4-one compound, finally, the target product was obtained by deketone and methylation reaction.
2. Other methods can be used, such as reacting pyrrole to generate 3-bromopyrrole, and then reacting with cyanoformate to form 2-Amino-3-cyano-4,5-dimethylpyrrole.
Safety Information:
2-Amino-3-cyano-4,5-dimethylpyrrole has limited safety information, but it is an organic compound and generally has certain toxicity and irritation. During operation and use, it is necessary to take necessary protective measures, such as wearing protective gloves, glasses and respiratory protection equipment, avoid contact with skin and inhalation. In addition, it should be operated in a well-ventilated place to avoid harmful gases or vapors. When stored, keep it well and away from ignition and oxidizing agents. In the event of an accident, immediately flush the affected area with plenty of water and seek medical help.
Last Update:2024-04-10 22:29:15