2-(4-bromophenyl)-1,10-Phenanthroline - Names and Identifiers
2-(4-bromophenyl)-1,10-Phenanthroline - Physico-chemical Properties
Molecular Formula | C18H11BrN2
|
Molar Mass | 335.2 |
Density | 1.485±0.06 g/cm3(Predicted) |
Melting Point | 187-189℃ |
Boling Point | 508.8±40.0 °C(Predicted) |
pKa | 4.48±0.10(Predicted) |
Physical and Chemical Properties | |
2-(4-bromophenyl)-1,10-Phenanthroline - Introduction
2-(4-bromophenyl)-1,10-phenanthroline is an organic compound containing a benzene ring and a phenanthroline ring in its chemical structure, and a bromine atom on the benzene ring. The following is a description of the nature, use, preparation and safety information of 2-(4-bromophenyl)-1,10-phenanthroline:
Nature:
-Appearance: 2-(4-bromophenyl)-1,10-phenanthroline is a solid substance with light yellow crystals.
-Solubility: It can be dissolved in some organic solvents, such as ethanol, dimethyl sulfoxide and chloroform.
-Stability: Stable at room temperature, but dangerous reactions may occur when encountering high temperatures, flames or oxidizing substances.
Use:
- 2-(4-bromophenyl)-1,10-phenanthroline is commonly used as a drug intermediate in the field of medicine, such as an intermediate for the synthesis of anticancer drugs.
-It can also be used as a raw material for the synthesis of organic light-emitting materials for the preparation of light-emitting diodes (LED) and other devices.
Method:
- 2-(4-bromophenyl)-1,10-phenanthroline can be prepared by reacting phenyl lithium with 4-bromobenzaldehyde to generate the corresponding imine. The imine is subsequently converted to 2-(4-bromophenyl)-1,10-phenanthroline by further reaction.
Safety Information:
- 2-(4-bromophenyl)-1,10-phenanthroline During operation, care should be taken to avoid inhalation, contact with skin and eyes, and keep away from fire and high temperature environment.
-It may cause irritation and damage to the human body, so safety equipment such as protective gloves, protective glasses and protective masks should be worn when using it.
-When handling this compound, appropriate industrial hygiene and safety measures should be taken to ensure that the operating environment is well ventilated.
Last Update:2024-04-09 20:49:11