2-(2-aminoethyl)pyridine
2-Pyridylethylamine
CAS: 2706-56-1
Molecular Formula: C7H10N2
2-(2-aminoethyl)pyridine - Names and Identifiers
| Name | 2-Pyridylethylamine |
| Synonyms | 2-Pyridylethylamine 2-PYRIDYLETHYLAMINE RARECHEM AL BW 0258 2-Pyridineethanamine 2-aminoethylpyridine 2-pyridineethanamine N-ethylpyridin-2-amine Betahistine Impurity 11 2-(2-pyridyl)ethylamine 2-(2-aminoethyl)pyridine 2-PYRIDIN-2-YL-ETHYLAMINE 2-(pyridin-2-yl)ethanamine 2-pyridin-2-ylethanaminium 2-(PYRIDIN-2-YL)ETHANAMINE 2-(pyridin-2-yl)ethanamine dihydrochloride |
| CAS | 2706-56-1 |
| EINECS | 220-295-1 |
| InChI | InChI=1/C7H10N2/c1-2-8-7-5-3-4-6-9-7/h3-6H,2H2,1H3,(H,8,9) |
2-(2-aminoethyl)pyridine - Physico-chemical Properties
| Molecular Formula | C7H10N2 |
| Molar Mass | 122.17 |
| Density | 1.021g/mLat 25°C(lit.) |
| Melting Point | 198-200 °C(Solv: ethanol (64-17-5)) |
| Boling Point | 92-93°C12mm Hg(lit.) |
| Flash Point | 213°F |
| Water Solubility | Soluble in water (partly), and most common polar solvent. Insoluble in non-polar solvents, and oils. |
| Vapor Presure | 0.125mmHg at 25°C |
| Appearance | Liquid |
| Specific Gravity | 1.021 |
| Color | Clear colorless to yellow |
| BRN | 111208 |
| pKa | pK1: 4.24(+2);pK2: 9.78(+1) (25°C,μ=0.05) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Sensitive | Air Sensitive |
| Refractive Index | n20/D 1.536(lit.) |
| Physical and Chemical Properties | Density 1.02 boiling point 92 ° C (12 torr) |
2-(2-aminoethyl)pyridine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | 2735 |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-34 |
| TSCA | Yes |
| HS Code | 29333990 |
| Hazard Class | 8 |
| Packing Group | III |
2-(2-aminoethyl)pyridine - Reference Information
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| Application | 2-(2-aminoethyl) pyridine is a pharmaceutical intermediate that can be obtained by reducing 2-(cyanomethyl) pyridine through sodium borohydride. It has been reported that it can be used to prepare arylcyclopropyl-amino-isoquinolinamide compounds. |
| Preparation | A solution of sodium borohydride (0.26g,7.00 mmol) in 30 mL of ether was added dropwise to a mixture of 2-(cyanomethyl) pyridine (0.80g,6.82 mmol) and AlCl3(0.93g,7.00 mmol). The solution was stirred at room temperature for 6 hours. Remove the solvent and extract the resulting mixture with hot isopropyl ether (3x30 mL). The organic layers were combined and the solvent was removed under reduced pressure to give 2-(2-aminoethyl) pyridine. |
Last Update：2024-04-10 22:29:15
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View History
2-(2-aminoethyl)pyridine
619295-68-0
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D(-)-Fructose
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1484815-73-7
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2-(4-methylphenyl)-2-oxo-1-phenylethyl 4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzoate
2,3-Bis(1-aziridinyl)-5-(4-tert-butylphenylsulfonyloxy)-1,4-naphthoquinone
1-Boc-3-(4-bromophenyl)-3-fluoroazetidine
41538-78-7
D(-)-Fructose