2-氨基-5-甲基噻唑(美洛昔康杂质)
2-Amino-5-methylthiazole
CAS: 7305-71-7
Molecular Formula: C4H6N2S
2-氨基-5-甲基噻唑(美洛昔康杂质) - Names and Identifiers
| Name | 2-Amino-5-methylthiazole |
| Synonyms | 423-800-5 T5N CSJ BZ D1 2-Amino-5-methylthia 5-Methyl-2-thiazolamine 2-Amino-5-methylthiazole 5-Methyl-2-aMinothiazole 2-Thiazolamine, 5-methyl- Thiazole, 2-amino-5-methyl- 5-methyl-1,3-thiazol-2-amine 2-Amino-5-methyl-1,3-thiazole 5-Methyl-1,3-thiazol-2-ylaMine Meloxicam Related Compound B (25 mg) (2-Amino-5-methyl-thiazole) |
| CAS | 7305-71-7 |
| EINECS | 423-800-5 |
| InChI | InChI=1/C4H6N2S/c1-3-2-6-4(5)7-3/h2H,1H3,(H2,5,6) |
| InChIKey | GUABFMPMKJGSBQ-UHFFFAOYSA-N |
2-氨基-5-甲基噻唑(美洛昔康杂质) - Physico-chemical Properties
| Molecular Formula | C4H6N2S |
| Molar Mass | 114.17 |
| Density | 1.258±0.06 g/cm3(Predicted) |
| Melting Point | 93-98 °C (lit.) |
| Boling Point | 232.5±9.0 °C(Predicted) |
| Flash Point | 94.4°C |
| Solubility | soluble in Methanol |
| Vapor Presure | 0.153-1.24Pa at 20-40℃ |
| Appearance | Yellow crystal |
| Color | Brown |
| BRN | 109603 |
| pKa | 5.42±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.618 |
| MDL | MFCD00078317 |
| Physical and Chemical Properties | Pale yellow crystalline powder. Melting point 94.0-96.0 °c. |
| Use | Used as an intermediate in the treatment of rheumatoid arthritis |
2-氨基-5-甲基噻唑(美洛昔康杂质) - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R48/22 - Harmful danger of serious damage to health by prolonged exposure if swallowed. R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S29 - Do not empty into drains. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
| UN IDs | 2811 |
| WGK Germany | 3 |
| HS Code | 29341000 |
| Hazard Note | Irritant/Keep Cold |
| Hazard Class | 9 |
| Packing Group | III |
2-氨基-5-甲基噻唑(美洛昔康杂质) - Reference Information
| LogP | 1.61 at 38℃ |
| surface tension | 72.6mN/m at 1.02g/L and 20 ℃ |
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| Use | use: the anti-inflammatory agent Meloxicam (Meloxicam) intermediate. used as an intermediate in the treatment of rheumatoid disease |
Last Update：2024-04-09 19:05:14
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View History
2-氨基-5-甲基噻唑(美洛昔康杂质)
1-(2-氯苯基)-2-异丙基氨基-乙醇
4-[(5-氯-4-甲基-2-磺酰苯基)偶氮]-3-羟基-2-萘甲酸钡
3-溴-6-甲基-6,7-二氢-5H-吡咯并[3,4-B]吡啶-5-酮
(2-氨基-5-氟苯基)氨基甲酸叔丁酯
Fmoc-Β-环己基-L-丙氨酸
(E)-己基(氨基(4-(((5-((3-氨基-3-氧丙基)(吡啶-2-基)氨基甲酰基)-1-甲基-1H-苯并[D]咪唑-2-基)甲基)氨基)苯基)亚甲基)氨基甲酸酯(达比加群酯杂质)
5-羟基-4-甲氧基-2-硝基苯甲酸乙酯
N-[芴甲氧羰基]-N-[(2-羟基-4-甲氧基苯基)甲基]甘氨酸
2-甲基-4-苯-1H-咪唑
1-(2-氯苯基)-2-异丙基氨基-乙醇
4-[(5-氯-4-甲基-2-磺酰苯基)偶氮]-3-羟基-2-萘甲酸钡
3-溴-6-甲基-6,7-二氢-5H-吡咯并[3,4-B]吡啶-5-酮
(2-氨基-5-氟苯基)氨基甲酸叔丁酯
Fmoc-Β-环己基-L-丙氨酸
(E)-己基(氨基(4-(((5-((3-氨基-3-氧丙基)(吡啶-2-基)氨基甲酰基)-1-甲基-1H-苯并[D]咪唑-2-基)甲基)氨基)苯基)亚甲基)氨基甲酸酯(达比加群酯杂质)
5-羟基-4-甲氧基-2-硝基苯甲酸乙酯
N-[芴甲氧羰基]-N-[(2-羟基-4-甲氧基苯基)甲基]甘氨酸
2-甲基-4-苯-1H-咪唑