2-氨基-4-甲氧基-5-(3-吗啉丙氧基)苯甲腈
Benzonitrile,4-methoxy-5-[3-(4-morpholinyl)propoxy]-2-nitro-
CAS: 675126-26-8
Molecular Formula: C15H19N3O5
2-氨基-4-甲氧基-5-(3-吗啉丙氧基)苯甲腈 - Names and Identifiers
2-氨基-4-甲氧基-5-(3-吗啉丙氧基)苯甲腈 - Physico-chemical Properties
| Molecular Formula | C15H19N3O5 |
| Molar Mass | 321.33 |
| Density | 1.29 |
| Melting Point | 127℃ |
| Boling Point | 522.3±50.0 °C(Predicted) |
| pKa | 6.96±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
2-氨基-4-甲氧基-5-(3-吗啉丙氧基)苯甲腈 - Reference Information
| biological activity | Gefitinib importance 1 is an impurity of Gefitinib. Gefitinib is a potent, orally active, selective EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 54 nM) and blocks EGFR autophosphorylation in EGF-stimulated tumor cells. Gefitinib can also induce autophagy in cells. Gefitinib has anti-tumor activity. |
| Use | gefitinib intermediate |
Last Update：2024-04-09 02:00:10
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View History
2-氨基-4-甲氧基-5-(3-吗啉丙氧基)苯甲腈
7-[[4-[[4-[[6-[(4-氨基苯甲酰)氨基]-1-羟基-3-磺酸基-2-萘基]偶氮]苯甲酰基]氨基]邻甲苯基]偶氮]萘-1,3-二磺酸三钠
[N-(2-氯苯基)-2-[(2-羟基-5-硝基苯基)偶氮]-3-氧代丁酰胺根合(2-)][3-羟基-4[(2-羟基-1-萘基)偶氮]-7-硝基-1-萘磺酸根合(3-)]-铬酸(2-)二钠
Asapiprant
BETA-DAMASCONE
5-硝基-2-(4-甲基-1-哌嗪基)吡啶
DNA, d(T-sp-C-G-sp-T-sp-C-G-sp-T-sp-T-sp-T-sp-T-sp-G-sp-A-sp-C-G-sp-T-sp-T-sp-T-sp-T-sp-G-sp-T-sp-C-G-sp-T-sp-T) (9CI)
4-氨基-6-氯-5-甲氧基嘧啶
2-甲基-4-碘-1-三苯甲游基咪唑
3-(叔丁基-二甲基-硅烷基OXY)-丙醛
7-[[4-[[4-[[6-[(4-氨基苯甲酰)氨基]-1-羟基-3-磺酸基-2-萘基]偶氮]苯甲酰基]氨基]邻甲苯基]偶氮]萘-1,3-二磺酸三钠
[N-(2-氯苯基)-2-[(2-羟基-5-硝基苯基)偶氮]-3-氧代丁酰胺根合(2-)][3-羟基-4[(2-羟基-1-萘基)偶氮]-7-硝基-1-萘磺酸根合(3-)]-铬酸(2-)二钠
Asapiprant
BETA-DAMASCONE
5-硝基-2-(4-甲基-1-哌嗪基)吡啶
DNA, d(T-sp-C-G-sp-T-sp-C-G-sp-T-sp-T-sp-T-sp-T-sp-G-sp-A-sp-C-G-sp-T-sp-T-sp-T-sp-T-sp-G-sp-T-sp-C-G-sp-T-sp-T) (9CI)
4-氨基-6-氯-5-甲氧基嘧啶
2-甲基-4-碘-1-三苯甲游基咪唑
3-(叔丁基-二甲基-硅烷基OXY)-丙醛