2,4-Difluoro-3-methoxybenzonitrile
2,4-Difluoro-3-methoxybenzonitrile
CAS: 220353-20-8
Molecular Formula: C8H5F2NO
2,4-Difluoro-3-methoxybenzonitrile - Names and Identifiers
| Name | 2,4-Difluoro-3-methoxybenzonitrile |
| Synonyms | NCR BF DF CO1 3-Methoxy-2,4-difluorobenzonitrile 2,4-Difluoro-3-methoxybenzonitrile |
| CAS | 220353-20-8 |
| InChI | InChI=1/C8H5F2NO/c1-12-8-6(9)3-2-5(4-11)7(8)10/h2-3H,1H3 |
2,4-Difluoro-3-methoxybenzonitrile - Physico-chemical Properties
| Molecular Formula | C8H5F2NO |
| Molar Mass | 169.13 |
| Density | 1.27g/cm3 |
| Melting Point | 44-46℃ |
| Boling Point | 233.4°C at 760 mmHg |
| Flash Point | 95°C |
| Vapor Presure | 0.0559mmHg at 25°C |
| Storage Condition | 2-8°C |
| Refractive Index | 1.485 |
| MDL | MFCD04115932 |
2,4-Difluoro-3-methoxybenzonitrile - Risk and Safety
| Hazard Class | 6.1 |
2,4-Difluoro-3-methoxybenzonitrile - Introduction
2. It is an organic compound with the chemical formula C8H5F2NO. The following is a description of some of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: colorless crystal
-Melting point: 57-61 ℃
-Boiling Point: 221-222 ℃
-Solubility: Soluble in organic solvents such as ether and ketone, solubility is lower than water
-aroma: with a special aromatic smell
Use:
2. It can be used in the preparation of intermediates and catalysts for organic synthesis. It has application value in medicine, pesticide, dye and other fields.
Method:
2. The preparation method of the pill can be carried out by the following steps:
1. 3-Methoxybenzonitrile is reacted with hydrofluoric acid to obtain 3-fluorobenzonitrile.
2.3-Fluorobenzonitrile is reacted with ammonium hydrogen fluoride to obtain 2,4-difluoro-3-fluoromethylbenzonitrile.
3., 4-difluoro-3-fluoromethylbenzonitrile reacts with iodomethane to obtain the final product 2.
Safety Information:
2. There is no obvious danger under normal operating conditions, but the following items still need to be paid attention:
-Unless otherwise specified, wear personal protective equipment such as gloves, glasses and protective clothing.
-Avoid inhalation or contact with skin and eyes, and pay attention to a good ventilation environment when using.
-If ingested or inhaled, consult a doctor immediately and show the package or label to your doctor.
-Store away from heat sources and open flames, and avoid contact with oxidants.
-Keep it safe and away from children and animals.
Please note that the above information is for reference only. When handling or using this compound, please follow the accurate information and instructions provided by the laboratory or manufacturer.
Nature:
-Appearance: colorless crystal
-Melting point: 57-61 ℃
-Boiling Point: 221-222 ℃
-Solubility: Soluble in organic solvents such as ether and ketone, solubility is lower than water
-aroma: with a special aromatic smell
Use:
2. It can be used in the preparation of intermediates and catalysts for organic synthesis. It has application value in medicine, pesticide, dye and other fields.
Method:
2. The preparation method of the pill can be carried out by the following steps:
1. 3-Methoxybenzonitrile is reacted with hydrofluoric acid to obtain 3-fluorobenzonitrile.
2.3-Fluorobenzonitrile is reacted with ammonium hydrogen fluoride to obtain 2,4-difluoro-3-fluoromethylbenzonitrile.
3., 4-difluoro-3-fluoromethylbenzonitrile reacts with iodomethane to obtain the final product 2.
Safety Information:
2. There is no obvious danger under normal operating conditions, but the following items still need to be paid attention:
-Unless otherwise specified, wear personal protective equipment such as gloves, glasses and protective clothing.
-Avoid inhalation or contact with skin and eyes, and pay attention to a good ventilation environment when using.
-If ingested or inhaled, consult a doctor immediately and show the package or label to your doctor.
-Store away from heat sources and open flames, and avoid contact with oxidants.
-Keep it safe and away from children and animals.
Please note that the above information is for reference only. When handling or using this compound, please follow the accurate information and instructions provided by the laboratory or manufacturer.
Last Update：2024-04-09 19:05:48
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View History
2,4-Difluoro-3-methoxybenzonitrile
Methyl 5-bromo-2-methoxy-4-methylbenzoate
303759-09-3
3-[(2E)-2-[(2-fluorophenyl)methylidene]hydrazinyl]-4H-1,2,4-triazin-5-one
PRUSSIAN BLUE SOLUBLE, FOR MICROSCOPY
cis-Dichloro (ethylenediaMine)platinuM(Ⅱ)
4-甲氧基-3-硝基苯乙铜
Dehydro Nicardipine HCl
5-[1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-YL]THIOPHENE-2-SULFONYL CHLORIDE
antimony, compound with samarium (1:1)
Methyl 5-bromo-2-methoxy-4-methylbenzoate
303759-09-3
3-[(2E)-2-[(2-fluorophenyl)methylidene]hydrazinyl]-4H-1,2,4-triazin-5-one
PRUSSIAN BLUE SOLUBLE, FOR MICROSCOPY
cis-Dichloro (ethylenediaMine)platinuM(Ⅱ)
4-甲氧基-3-硝基苯乙铜
Dehydro Nicardipine HCl
5-[1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-YL]THIOPHENE-2-SULFONYL CHLORIDE
antimony, compound with samarium (1:1)