2,4-Dichloro-7-methoxyquinoline - Names and Identifiers
2,4-Dichloro-7-methoxyquinoline - Physico-chemical Properties
Molecular Formula | C10H7Cl2NO
|
Molar Mass | 228.07 |
Density | 1.384±0.06 g/cm3(Predicted) |
Melting Point | 132-133 °C(Solv: ethanol (64-17-5)) |
Boling Point | 327.9±37.0 °C(Predicted) |
Flash Point | 152.1°C |
Vapor Presure | 0.000374mmHg at 25°C |
pKa | -0.79±0.50(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.63 |
2,4-Dichloro-7-methoxyquinoline - Introduction
2, is an organic compound with the chemical formula C10H6Cl2NO. It is a yellow crystalline solid, soluble in organic solvents such as ethanol and dimethylformamide, and insoluble in water.
2, has a wide range of applications in the field of pharmacy. It is used as an intermediate in the synthesis of antimalarial drugs for the synthesis of drugs such as chloroquine and isofluoroquinoline. It also has antibacterial and antifungal activities, so it is used in the development of new drugs.
2, The preparation of the pill can be carried out by a variety of methods. A common method is to react 2,4-dichloroquinoline with thionyl chloride and then with methanol to give 2,4-dichloroquinoline. Other methods include alkene barbeate ketonization reactions, acid catalyzed methanation reactions, and the like.
Regarding safety information, 2. It is stable under normal circumstances, but it is toxic and exposure can cause health hazards. It is necessary to pay attention to protective measures during use, such as wearing protective gloves, goggles and protective clothing. In addition, avoid inhaling its vapors or contact with skin and eyes. Follow chemical safety practices during storage and handling. If necessary, refer to the relevant safety data sheet or consult a professional for more detailed safety information.
Last Update:2024-04-09 20:52:54