2,3-Difluoro-4-iodopyridine - Names and Identifiers
2,3-Difluoro-4-iodopyridine - Physico-chemical Properties
Molecular Formula | C5H2F2IN
|
Molar Mass | 240.98 |
Density | 2.129 |
Melting Point | 66-68 °C |
Boling Point | 213 °C |
Flash Point | 82 °C |
Vapor Presure | 0.248mmHg at 25°C |
pKa | -4.24±0.18(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.572 |
2,3-Difluoro-4-iodopyridine - Risk and Safety
2,3-Difluoro-4-iodopyridine - Introduction
2,3-Difluoro-4-iodo-pyridine is an organic compound with the chemical structure of C5H3F2IN. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2,3-Difluoro-4-iodo-pyridine is a white crystalline solid.
-Melting point: about 107-110 degrees Celsius.
-Boiling point: about 205 degrees Celsius.
-Density: about 2.15g/cm³.
-Solubility: 2,3-Difluoro-4-iodo-pyridine is soluble in organic solvents such as chloroform, methanol and ethanol.
Use:
2,3-Difluoro-4-iodo-pyridine can be used as an important intermediate in organic synthesis. It is widely used in the synthesis of other drugs and pesticides, and can also be used to synthesize biologically active compounds.
Preparation Method:
Generally, the synthesis of 2,3-Difluoro-4-iodo-pyridine is obtained by reacting iodobenzene with chlorotetrafluoroacetic acid (ClF2CCOOH) in the presence of potassium carbonate.
Safety Information:
- 2,3-Difluoro-4-iodo-pyridine is safe to store at room temperature, but should avoid exposure to direct sunlight.
-May cause irritation to the eyes, skin and respiratory system, so wear appropriate personal protective equipment during operation.
-Inhalation, ingestion or skin contact may cause health hazards, so you should pay attention to protective measures when using, and prevent it from entering the human body.
-When a leak occurs, avoid inhaling its vapor and use appropriate emergency treatment methods.
-During use and storage, be sure to comply with relevant chemical management regulations and safe operating procedures.
Last Update:2024-04-09 20:49:11