1H-Indazole-1-carboxylicacid,3-(broMoMethyl)-,1,1-diMethylethylester - Names and Identifiers
Name | 1H-Indazole-1-carboxylic acid, 3-(bromomethyl)-, 1,1-dimethylethylester
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Synonyms | 1-Boc-3-(broMoMethyl)-1H-indazole 3-(Bromomethyl)-1H-indazole,N1-BOCprotected TERT-BUTYL 3-(BROMOMETHYL)-1H-INDAZOLE-1-CARBOXYLATE 3-BroMoMethyl-indazole-1-carboxylic acid tert-butyl ester 1H-Indazole-1-carboxylicacid,3-(broMoMethyl)-,1,1-diMethylethylester 1H-Indazole-1-carboxylic acid, 3-(bromomethyl)-, 1,1-dimethylethylester
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CAS | 174180-42-8
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1H-Indazole-1-carboxylicacid,3-(broMoMethyl)-,1,1-diMethylethylester - Physico-chemical Properties
Molecular Formula | C13H15BrN2O2
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Molar Mass | 311.17 |
Storage Condition | Room Temprature |
1H-Indazole-1-carboxylicacid,3-(broMoMethyl)-,1,1-diMethylethylester - Introduction
acid, 3-(bromomethyl)-, 1,1-dimethylethylester is an organic compound with the chemical formula C15H17BrNO2 and molecular weight of 319.21. The following is a description of its nature, use, preparation and safety information:
Nature:
acid, 3-(bromomethyl)-, 1,1-dimethylethylester is a solid, colorless or yellowish crystal. It is soluble in ethanol, dimethyl sulfoxide and chloroform at room temperature, and insoluble in water. The compound has high thermal stability.
Use:
acid, 3-(bromomethyl)-, 1,1-dimethylethylester is a commonly used intermediate compound in organic synthesis. It can be used as a raw material for the synthesis of indole derivatives and is widely used in the fields of medicine and pesticide. In addition, it can also be used to prepare protease inhibitors, bioactive compounds and fluorescent probes.
Method:
The preparation of acid, 3-(bromomethyl)-, 1,1-dimethylethylester is generally carried out by the following steps: First, under acidic conditions, the reaction of N-Boc-3-bromomethylpyruvate with indole gives acid, 3-(bromomethyl)-, 1,1-dimethylethylester. The desired product can then be obtained by structural modification thereof (e. G., acid hydrolysis, base deprotection, etc.).
Safety Information:
The acid, 3-(bromomethyl)-, 1,1-dimethylethylester needs to take safety measures when carrying, storing and handling, avoiding inhalation, contact with skin and eyes. Wear protective glasses, protective gloves and protective clothing during operation. If you come into contact with this substance, rinse immediately with plenty of water and seek medical help. In addition, the compound should be stored in a dry, dark, well-ventilated place, away from fire and oxidizing agents.
Last Update:2024-04-09 21:01:54