194805-07-7 - Names and Identifiers
Name | 7-Bromo-1-Cyclopropyl-8-(Difluoromethoxy)-1,4-Dihydro-4-Oxo-3-Quinolinecarboxylic Acid Ethyl Ester
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Synonyms | 7-Bromo-1-Cyclopropyl-8-(Difluoromethoxy)-1,4-Dihydro-4-Oxo-... 7-bromo-1-cyclopropyl-8-(difluoromethoxy)-2-ethyl-4-oxo-3-quinolinecarboxylate Ethyl-7-bromo-1-cyclopropyl-8-difluoromethoxy-1,4-dihydro-4-oxoquinoline-3-carboxylate ethyl 7-bromo-1-cyclopropyl-8-difluoromethoxy-4-oxo-1,4-dihydro-3-quinoline-carboxylate ETHYL 7-BROMO-1-CYCLOPROPYL-8-(DIFLUOROMETHOXY)-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLATE Ethyl 7-Bromo-1-Cyclopropyl-8-(Difluoromethoxy)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate Ethyl 7-Bromo-1-Cyclopropyl-8-(Difluoromethoxyl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylate 7-BROMO-1-CYCLOPROPYL-8-(DIFLUOROMETHOXY)-1,4-DIHYDRO-4-OXO-3-QUINOLINECARBOXYLIC ACID ETHYL ESTER 7-Bromo-1-Cyclopropyl-8-(Difluoromethoxy)-1,4-Dihydro-4-Oxo-3-Quinolinecarboxylic Acid Ethyl Ester 3-Quinolinecarboxylic acid, 7-bromo-1-cyclopropyl-8-(difluoromethoxy)-1,4-dihydro-4-oxo-, ethyl ester
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CAS | 194805-07-7
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InChI | InChI=1/C16H14BrF2NO4/c1-2-23-15(22)10-7-20(8-3-4-8)12-9(13(10)21)5-6-11(17)14(12)24-16(18)19/h5-8,16H,2-4H2,1H3 |
194805-07-7 - Physico-chemical Properties
Molecular Formula | C16H14BrF2NO4
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Molar Mass | 402.19 |
Density | 1.624 |
Boling Point | 477.4±45.0 °C(Predicted) |
Flash Point | 242.546°C |
Vapor Presure | 0mmHg at 25°C |
pKa | -4.46±0.40(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.593 |
194805-07-7 - Introduction
7-bromo-1-8-(difluoromoxy)-1, cyloethyl Ester is an organic compound with the chemical formula C14H14BrF2NO4. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 7-Bromo-1-Cyclopropyl-8-(Difluoromethoxy)-1, Acid Ethyl Ester appears as a white crystalline solid.
-Solubility: It has good solubility in common organic solvents.
-Melting point: about 175-180 ℃.
Use:
-7-bro-1-cyclopropyl-8-(Difluoromethoxy)-1, Acid Ethyl Ester, as an organic synthesis, is commonly used in the field of pharmaceutical chemistry.
-It can be used to synthesize biologically active compounds, such as drugs, pesticides, etc.
Method:
7-bro-1-cycloprocyl-8-(Difluoromethoxy)-1, the specific synthesis method of Acid Ester may vary depending on the experimental conditions and reaction system, but generally includes the following:
1. Under appropriate conditions, some of the starting materials are reacted with bromoacetic anhydride to give ethyl 7-bromo-1, 4-dihydro-4-oxoquinoline-3-carboxylate.
2. The product obtained in the first step is reacted with fluorine gas to give ethyl 7-bromo-8-difluoromethoxy-1, 4-dihydro-4-oxoquinoline-3-carboxylate.
Safety Information:
-7-bro-1-cyclopropyl-8-(Difluoromethoxy)-1, Acid Ethyl Ester has limited safety information, so appropriate protective measures should be taken during manipulation and storage.
-It may be irritating to the eyes, skin and respiratory system, so wear appropriate protective equipment such as gloves, goggles and respiratory protectors during operation.
-Proper laboratory practices should be followed when using, storing and handling the compound, and adequate ventilation should be provided for personal safety.
Last Update:2024-04-09 20:49:11