Name | (25S)-5β-Spirostane-1β,3β,4β,5-tetrol |
Synonyms | Convallagenin B (25S)-5β-Spirostane-1β,3β,4β,5-tetrol Spirostan-1,3,4,5-tetrol, (1β,3β,4β,5β,25S)- |
CAS | 17934-59-7 |
Molecular Formula | C27H44O6 |
Molar Mass | 464.63 |
Storage Condition | 2-8℃ |
Introduction | , according to the general method of plant taxonomy, the groups of closely related plants are divided, including convalaria, reineckiia, Herba Herba, the genus cericoides, Rohdea, Tupistra, and Aspidistra are single species except for the genus canicoides and the genus aspidia. Steroidal saponins is an important chemical component of Chinese herbal medicine, which has a wide range of pharmacological activities, such as protecting cardiovascular and cerebrovascular, anti-bacterial, anti-inflammatory, anti-tumor, its medicinal value and development potential have been paid more and more attention. Especially in the cardiac and cerebral vascular activity is remarkable, some of the total saponins of traditional Chinese medicine have been developed, For example, Diao xinxuekang capsule, gongxuening, xinnao Shutong and Changlong guanxinning. Since the 2050's, some scholars have carried out basic research on the chemical constituents of the plants of the Lily of the Lily, and expounded the genetic relationship of each genus from the point of view of chemical composition, it is clear that the plants of lily of the valley contain steroidal saponins such as the saponin B.|
pharmacological action | The saponins of lily of the Valley, in the study of the hypoglycemic effect of the grass, it was found that the total saponins of the grass, including the saponin B, can reduce the blood glucose level of the diabetic rats induced by streptozotocin, and significantly improve the sugar tolerance ability of diabetic rats, however, it has no effect on the blood glucose level of normal rats; The extract of open arrow, including saponin B, can improve the activity of alcohol dehydrogenase, aldehyde dehydrogenase, superoxide dismutase and glutathione peroxidase, and accelerate the metabolism of ethanol in the body, reduces the accumulation of free radicals in the body, reduces the content of lipid peroxides. |