17481-06-0

17481-06-0 - Names and Identifiers

Name	N-Acetyl-DL-4-fluorophenylalanine
Synonyms	Ac-Phe(4-F)-OH AC-P-FLUORO-DL-PHE-OH LABOTEST-BB LT00012638 N-acetyl-4-fluorophenylalanine ACETYL-4-FLUORO-DL-PHENYLALANINE N-Acetyl-DL-4-fluorophenylalanine N-acetyl-4-fluoro-L-phenylalanine N-acetyl-4-fluoro-D-phenylalanine (±)-N-Acetyl-4-fluorophenylalanine ACETYL-DL-P-FLUOROPHENYLALANINE, N- N-Acetyl-3-(4-fluorophenyl)-DL-alanine rac-(R)-N-Acetyl-2-(4-fluorobenzyl)glycine (2S)-2-(acetylamino)-3-(4-fluorophenyl)propanoate (2R)-2-(acetylamino)-3-(4-fluorophenyl)propanoate rac-(R)-α-(Acetylamino)-4-fluorobenzenepropionic acid
CAS	17481-06-0
EINECS	241-495-5
InChI	InChI=1/C11H12FNO3/c1-7(14)13-10(11(15)16)6-8-2-4-9(12)5-3-8/h2-5,10H,6H2,1H3,(H,13,14)(H,15,16)/p-1/t10-/m1/s1

17481-06-0 - Physico-chemical Properties

Molecular Formula	C11H12FNO3
Molar Mass	225.22
Density	1.2317 (estimate)
Melting Point	150-153°C(lit.)
Boling Point	458.9°C at 760 mmHg
Flash Point	231.3°C
Vapor Presure	3.25E-09mmHg at 25°C
BRN	3206105
Storage Condition	Sealed in dry,Room Temperature
MDL	MFCD00017983

17481-06-0 - Risk and Safety

Hazard Symbols	Xi - Irritant
Safety Description	24/25 - Avoid contact with skin and eyes.
WGK Germany	3
TSCA	Yes
Hazard Note	Irritant/Keep Cold

17481-06-0 - Introduction

N-Acetyl-DL-4-fluorophenylalanine is an organic compound with the chemical formula C10H11FNO4. Here are some information about its nature, use, formulation and safety:

Nature:
-Appearance: N-Acetyl-DL-4-fluorophenylalanine is a solid, usually white or white-like crystalline powder.
-Solubility: Its solubility in water is low, but it is soluble in some organic solvents, such as methanol and dimethyl sulfoxide.
-Melting point: The melting point of the N-Acetyl-DL-4-fluorophenylalanine is about 145-150°C.

Use:
- N-Acetyl-DL-4-fluorophenylalanine is an important pharmaceutical intermediate that can be used to synthesize other drugs. It is commonly used in the manufacture of biologically active organic compounds, such as synthetic pharmaceutical raw materials and drug precursors.

Method:
-The preparation method of the N-Acetyl-DL-4-fluorophenylalanine can be carried out through the following steps:
1. First, 4-fluorobenzene propionic acid and acid chloride were selected as raw materials to react to obtain the acylated product.
2. Then, the acylated product is esterified with acetic anhydride under appropriate conditions to obtain N-Acetyl-DL-4-fluorophenylalanine.

Safety Information:
-The safety assessment of the N-Acetyl-DL-4-fluorophenylalanine is limited, so caution is required during use and handling.
-Avoid inhalation, ingestion, skin contact and dust generation during handling.
-Use in accordance with appropriate safety practices and with appropriate personal protective equipment such as gloves, glasses and lab coats.
-Keep it in a dry, well-ventilated place during storage and handling.
-In case of inhalation or skin contact, rinse immediately with plenty of water and seek medical help. If eye contact occurs, immediately flush eyes with plenty of water and seek medical help.

Please note that this information is for reference only. Specific experimental operations and precautions for use should be carried out in accordance with relevant laboratories and safety guidelines.

Last Update：2024-04-09 21:01:54