16285-26-0 - Names and Identifiers
16285-26-0 - Physico-chemical Properties
Molecular Formula | C12H10N2O2
|
Molar Mass | 214.22 |
Density | 1.246±0.06 g/cm3(Predicted) |
Melting Point | 166-167 °C(Solv: ethanol (64-17-5)) |
Boling Point | 502.4±50.0 °C(Predicted) |
pKa | 12.14±0.40(Predicted) |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD00102818 |
16285-26-0 - Risk and Safety
16285-26-0 - Introduction
2-Furan-2-yl-2, (2-furan-2-yl-2, 3-dihydroquinazolin -4-one) is an organic compound. Its chemical structure contains furan ring and quinazoline ring. The following is a description of the properties, uses, preparation and safety information of this compound:
Nature:
-Appearance: 2-Furan-2-yl-2, is white solid or crystalline powder.
-Melting point: about 150-153 ℃.
-Solubility: 2-Furan-2-yl-2, insoluble in water, but can be dissolved in some organic solvents, such as alcohols, ethers, etc.
-Chemical properties: It can occur a series of organic reactions, such as oxidation reaction, reduction reaction, substitution reaction, etc.
Use:
-Drug research: 2-Furan-2-yl-2, is an intermediate compound that can be used to synthesize other biologically active compounds. It is widely used in the field of drug research for the development of anti-tumor, anti-inflammatory, antibacterial and antiviral drugs.
Preparation Method:
The preparation method of 2-Furan-2-yl-2 can be described as follows:
1. First, the corresponding substituted acetophenone (substituted) and 2-aminobenzoic acid (2-aminobenzoic acid) were condensed under alkaline conditions to obtain the corresponding quinazolin-2-one compound (quinazolin-2-ones).
2. Then, 2-Furan-2-yl-2 was obtained by heating and reacting the quinazolin-2-one compound and furan phthalein (furfuryl alcohol) under acidic conditions.
Safety Information:
-It is an organic compound and should be handled, stored and used with appropriate precautions, including gloves, goggles and proper ventilation.
-Avoid contact with skin and inhalation of particles or vapors during use to avoid irritation or adverse health effects.
-Because specific toxicity data may not be sufficient, good laboratory practice and safe operating guidelines should be followed at the time of use.
Last Update:2024-04-09 21:01:54