157311-42-7 - Names and Identifiers
157311-42-7 - Physico-chemical Properties
Molecular Formula | C15H21NO4
|
Molar Mass | 279.33 |
Storage Condition | 2-8°C |
157311-42-7 - Upstream Downstream Industry
157311-42-7 - Introduction
Ethyl 4-(((tert-butoxycarbonyl)amino)methyl)benzoate, also known as 4-(((tert-butoxycarbonyl)amino)methyl) phenyl acetate, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless to light yellow solid
-molecular formula: C16H21NO5
-relative molecular mass: 311.34g/mol
-Melting point: 49-51 ° C
-Boiling Point: 187-189 ° C
-Solubility: Soluble in dimethylformamide, methanol and ethanol
Use:
- Ethyl 4-(((tert-butoxycarbonyl)amino)methyl)benzoate is often used as a reagent and intermediate in organic synthesis.
-It can be used to synthesize drugs, pesticides, dyes and other organic compounds.
Method:
The synthesis of-Ethyl 4-(((tert-butoxycarbonyl)amino)methyl)benzoate is usually carried out by the following steps:
1. Benzyl Ester is reacted with dimethyl carbonate to obtain dimethyl benzoate.
2. Esterification of dimethyl benzoate with methyl cyanoformate in the presence of sodium hydroxide to give ethyl benzoate (sodium oxide).
3. Benzoic acid (sodium oxide) Ethyl ester is reacted with BOC-methylamine to generate Ethyl 4-(((tert-butoxycarbonyl)amino)methyl)benzoate.
Safety Information:
- Ethyl 4-(((tert-butoxycarbonyl)amino)methyl)benzoate has certain safety under regular operating conditions.
-However, it can be irritating to the eyes, skin and respiratory system, so wear appropriate personal protective equipment such as gloves and safety glasses during operation.
-At the same time, as an organic solvent, it should avoid contact with flammable substances and be used in a well-ventilated area.
Last Update:2024-04-09 21:11:58