(S)-N-4-BOC-N-1-CBZ-2-PIPERAZINE chemical ACID, also known as (Tosyl-L-Phenylalanine) chemical Ketone, is an organic compound. Its structural formula is C23H27NO6S.
Nature:
1. Appearance: white solid.
2. Melting Point: about 80-85 ° C.
3. Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide (DMSO) and dichloromethane. Insoluble in water.
Use:
(S)-N-4-BOC-N-1-CBZ-2-PIPERAZINE CARBOXYLIC ACID is mainly used as an intermediate of Chiral reagents and catalysts in organic synthesis reactions. It can be used to prepare biologically active compounds, such as drugs and organic photosensitizers.
Method:
(S)-The preparation method of N-4-BOC-N-1-CBZ-2-PIPERAZINE carboxy ACID is more complicated and generally includes the following steps:
1. React (S)-phenylpropanacetic acid with P-Toluenesulfonyl chloride to obtain (S)-phenylpropanacetic acid p-Toluenesulfonyl ester.
2. The resulting ester is reacted with Di (butyl) Di (methylene) dicarboxylate to give (S)-4-tert-butoxycarbonyl-1-benzyloxycarbonyl-2-methylenecyclobutyl ester.
3. Finally, through heating and hydrolysis reaction, (S)-N-4-BOC-N-1-CBZ-2-PIPERAZINE CARBOXYLIC ACID is obtained.
Safety Information:
(S)-N-4-BOC-N-1-CBZ-2-PIPERAZINE boxylic ACID has no apparent hazard reports during normal use. However, during the operation, attention should be paid to following the safety operating procedures of the chemical laboratory, wearing appropriate personal protective equipment (such as gloves, glasses, etc.), and avoiding inhalation, intake or contact with skin. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.