149690-12-0 - Names and Identifiers
Name | (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride
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Synonyms | LCZ698 LCZ696 Intermediate2 (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate HCl (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate hydrochloride (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride
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CAS | 149690-12-0
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EINECS | 695-675-7 |
149690-12-0 - Physico-chemical Properties
Molecular Formula | C20H26ClNO2
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Molar Mass | 347.87894 |
Melting Point | 155 - 162°C |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | White to Off-White |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Stability | Hygroscopic |
149690-12-0 - Introduction
(2R,4S)-5-([1,1 '-biphenyl]-4-amino-2-methylpentanoic acid ethyl ester hydrochloride is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Usually a white crystalline solid
-Molecular formula: C18H22ClNO2
-Molecular weight: 325.83g/mol
-Melting point: about 125-128°C
-Solubility: Slightly soluble in water, better solubility in organic solvents
Use:
(2R,4S)-5-([1,1 '-biphenyl]-4-amino -2-methyl pentanoic acid ethyl ester hydrochloride is commonly used in the field of medicine, has certain pharmacological activity and biological activity. It may be used as an intermediate of angiotensin converting enzyme inhibitors (ACE inhibitors) for the treatment of hypertension, heart failure and other cardiovascular and cerebrovascular diseases.
Preparation Method:
Ethyl (2R,4S)-5-([1,1 '-biphenyl]-4-amino-2-methylpentanoate hydrochloride is typically prepared by chemical synthesis. A specific preparation method may include steps such as reaction and crystallization of the compound through successive synthetic routes.
Safety Information:
- (2R,4S)-5-([1,1 '-biphenyl]-4-amino-2-methylpentanoic acid ethyl ester hydrochloride should be operated and handled under suitable laboratory conditions to avoid Contact with skin and inhalation. Personal protective equipment such as laboratory gloves, protective glasses and laboratory coats should be worn during use.
-It may be harmful to the environment and needs to be properly handled and disposed. Observe local regulations and environmental regulations at the time of disposal.
-Please refer to the relevant safety data sheets and biosafety level guidelines when using and storing to ensure safe operation.
Last Update:2024-04-09 02:00:49