1415407-60-1
(4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone
CAS: 1415407-60-1
Molecular Formula: C25H25N3O2
1415407-60-1 - Names and Identifiers
1415407-60-1 - Physico-chemical Properties
| Molecular Formula | C25H25N3O2 |
| Molar Mass | 399.48 |
| Density | 1.253±0.06 g/cm3(Predicted) |
| Boling Point | 564.5±50.0 °C(Predicted) |
| Solubility | Soluble in DMSO |
| pKa | 6.35±0.20(Predicted) |
| Storage Condition | -20℃ |
| Use | TC-G 1005 is a potent and selective TGR5 (GPBAR1) agonist. |
| Target | IC50: 0.72 nM (hTGR5); 6.2 nM (mTGR5) |
1415407-60-1 - Reference
| Reference Show more | 1: Duan H, Ning M, Chen X, Zou Q, Zhang L, Feng Y, Zhang L, Leng Y, Shen J. Design, synthesis, and antidiabetic activity of 4-phenoxynicotinamide and 4-phenoxypyrimidine-5-carboxamide derivatives as potent and orally efficacious TGR5 agonists. J Med Chem. 2012 Dec 13;55(23):10475-89. doi: 10.1021/jm301071h. Epub 2012 Nov 29. PubMed PMID: 23148522. |
1415407-60-1 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.503 ml | 12.516 ml | 25.032 ml |
| 5 mM | 0.501 ml | 2.503 ml | 5.006 ml |
| 10 mM | 0.25 ml | 1.252 ml | 2.503 ml |
| 5 mM | 0.05 ml | 0.25 ml | 0.501 ml |
Last Update：2024-01-02 23:10:35
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Product Name: TC-G 1005 Visit Supplier Webpage Request for quotationCAS: 1415407-60-1
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: TC-G1005 Visit Supplier Webpage Request for quotationCAS: 1415407-60-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
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Product Name: TC-G 1005 Visit Supplier Webpage Request for quotationCAS: 1415407-60-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
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Spot supply
Product Name: (4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone Visit Supplier Webpage Request for quotationCAS: 1415407-60-1
Tel: 18301782025
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View History
1415407-60-1
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