141236-47-7 - Names and Identifiers
141236-47-7 - Physico-chemical Properties
Molecular Formula | C9H6ClNO3
|
Molar Mass | 211.6 |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD12198078 |
141236-47-7 - Risk and Safety
141236-47-7 - Introduction
(2E)-3-(2-Nitrophenyl)acryloyl chloride is an organic compound whose chemical formula is C9H5ClNO3. The following are some information about the properties, uses, preparation and safety of this compound:
Nature:
-Appearance: Colorless to light yellow crystal
-Melting point: 70-72°C
-Boiling Point: 210-212°C(1 mmHg)
-Solubility: Soluble in organic solvents such as ether, dichloromethane, insoluble in water
Use:
(2E)-3-(2-Nitrophenyl)acryloyl chloride is mainly used in the synthesis of carboxylic acid derivatives in organic synthesis. It can be used for the synthesis of carboxyl-containing drugs, pesticides, dyes and bioactive molecules.
Preparation Method:
The preparation of (2E)-3-(2-Nitrophenyl)acryloyl chloride can usually be carried out by the following steps:
1.2-nitrobenzoic acid is reacted with an acylating agent (such as thionyl chloride) to generate 2-nitrobenzoyl chloride.
2. reacting 2-nitrobenzoyl chloride with acryloyl chloride to generate (2E)-3-(2-Nitrophenyl)acryloyl chloride.
Safety Information:
- (2E)-3-(2-Nitrophenyl)acryloyl chloride irritant to the eyes, skin and respiratory tract. Avoid direct contact with skin and eyes and ensure adequate ventilation.
-Wear appropriate personal protective equipment such as goggles, gloves and protective clothing when using.
-Avoid inhaling dust and solution vapors and avoid swallowing.
-Operate under safe ventilation and avoid contact with oxidants and combustibles.
-In case of contact or inhalation, immediately wash or seek medical treatment.
Last Update:2024-04-09 02:00:57