1365531-85-6 - Names and Identifiers
Name | (S)-2,2'-Bis[bis(3,5-trifluoromethylphenyl)phosphino]-4,4',6,6'-tetramethoxy)-1,1'-biphenyl
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Synonyms | (S)-2,2'-Bis[bis(3,5-trifluoroMethylphenyl)phosphino]-4,4',6,6'-tetraMethoxybiphenyl (S)-2,2'-Bis[bis(3,5-trifluoromethylphenyl)phosphino]-4,4',6,6'-tetramethoxy)-1,1'-biphenyl (S)-2,2'-Bis[bis(3,5-trifluoroMethylphenyl)phosphino]-4,4',6,6'-tetraMethoxybiphenyl (S)-BTFM-Garphos Phosphine, 1,1'-[(1S)-4,4',6,6'-tetramethoxy[1,1'-biphenyl]-2,2'-diyl]bis[1,1-bis[3,5-bis(trifluoromethyl)phenyl]-
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CAS | 1365531-85-6
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1365531-85-6 - Physico-chemical Properties
Molecular Formula | C48H28F24O4P2
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Molar Mass | 1186.66 |
Boling Point | 722.5±60.0 °C(Predicted) |
Water Solubility | Insoluble in water. |
Appearance | crystal |
Color | white |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Sensitive | Air Sensitive |
1365531-85-6 - Introduction
(S)-2,2 '-Bis[bis(3,5-trifluoromethylphenyl)phosphino]-4,4',6,6 '-tetramethoxy)-1,1'-biphenyl, abbreviated (S)-BINAP, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
(S)-BINAP is a colorless crystalline solid with a specific chiral structure. Its melting point is around 150-154 degrees Celsius. The compound is soluble in common solvents and has good thermal stability.
Use:
(S)-BINAP is an important chiral ligand, which is widely used in metal-catalyzed reactions. It can form complexes with platinum, rhodium, palladium and other transition metals to participate in asymmetric catalytic reactions. These reactions include asymmetric hydrogenation, asymmetric oxidation, asymmetric randomization and other important organic synthesis reactions.
Preparation Method:
The preparation method of (S)-BINAP is more complicated and can be synthesized through multi-step reactions. A common synthetic method is to obtain the target product by a decomposition reaction of a diphenyl ester.
Safety Information:
(S)-BINAP is generally stable and non-flammable under normal conditions of use. However, decomposition reactions may occur at high temperatures to produce toxic gases. Therefore, when handling and operating, you need to pay attention to the use of appropriate protective equipment, such as gloves and goggles, and operate in a well-ventilated place.
Summary:
(S)-BINAP is an important chiral compound commonly used in metal-catalyzed reactions. Its preparation is more complicated and requires attention to safe operation. The wide application of this compound provides an important chiral ligand for organic synthesis.
Last Update:2024-04-09 21:32:45