13452-14-7

13452-14-7 - Names and Identifiers

Name	2-Methyl-1,3-benzoxazole-6-carboxylic acid
Synonyms	1,2-Ethanediamine,5-phenyl- 2-Methylbenzoxazole-6-carboxylic Acid 2-Methyl-6-benzoxazole carboxylic acid 6-Benzoxazolecarboxylic acid, 2-methyl- 2-METHYLBENZO[D]OXAZOLE-6-CARBOXYLIC ACID 2-Methyl-1,3-benzoxazole-6-carboxylic acid Benzenepropanoicacid,7-methyl-β-oxo-,ethylester
CAS	13452-14-7
InChI	InChI=1/C9H7NO3/c1-5-10-7-3-2-6(9(11)12)4-8(7)13-5/h2-4H,1H3,(H,11,12)

13452-14-7 - Physico-chemical Properties

Molecular Formula	C9H7NO3
Molar Mass	177.16
Density	1.38g/cm³
Melting Point	>230°C (dec.)
Boling Point	353.462°C at 760 mmHg
Flash Point	167.568°C
Solubility	DMSO (Slightly, Heated), Methanol (Slightly, Heated)
Vapor Presure	0mmHg at 25°C
Appearance	Solid
Color	Pale Beige
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.64
MDL	MFCD07787266

13452-14-7 - Introduction

2-methyl -1, 3-benzoxazole-6-carboxylic acid is an organic compound with the formula C10H7NO3. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance: 2-methyl -1, 3-benzoxazole-6-carboxylic acid is colorless crystal or solid powder.
-Solubility: It is almost insoluble in water, but has good solubility in organic solvents such as ethanol, dimethyl sulfoxide, etc.

Use:
-Chemical synthesis: 2-methyl -1, 3-benzoxazole-6-carboxylic acid can be used as an intermediate in organic synthesis and is widely used in pesticide, medicine and dye industries.
-Pesticide: It can be used as a synthetic raw material for ciprofloxacin and other fungicides and herbicides, and has good antibacterial and insecticidal activity.
-Medicine: 2-methyl -1, 3-benzoxazole-6-carboxylic acid has certain inhibitory effects on cell growth and DNA replication, so it may have potential applications in drug development.
-Dye: It can be used as a synthetic intermediate for organic dyes and used in the dye industry.

Preparation Method:
- 2-methyl -1,3-benzoxazole -6-carboxylic acid synthesis method is more, common methods include: benzoxazole derivatives with methylating reagent reaction, or through the methyl diamine acid and hydroxyl compounds with condensation reaction. The specific synthetic route will vary depending on the desired product and reaction conditions.

Safety Information:
- 2-methyl -1, 3-benzoxazole-6-carboxylic acid has low toxicity, but it is still necessary to pay attention to safe operation.
-When using, avoid direct contact with the skin and avoid inhaling its dust and vapor.
-Observe relevant safety regulations during handling and storage, such as wearing personal protective equipment (e. g. gloves, goggles, etc.).
-If taken by mistake or inhaled, seek medical attention immediately. Any abnormal condition after contact with chemicals should seek medical help immediately.

Last Update：2024-04-09 19:05:46