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13224-84-5

5-TRIMETHYLSILYL-4-PENTYN-1-OL

CAS: 13224-84-5

Molecular Formula: C8H16OSi

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13224-84-5 - Names and Identifiers

Name 5-TRIMETHYLSILYL-4-PENTYN-1-OL
Synonyms TIMTEC-BB SBB009060
TriMethylsilyl-4-prnty
5-TRIMETHYLSILYL-4-PENTYN-1-OL
5-Trimethylsilyl-4-prntyn-1-ol
5-(Trimethylsilyl)pent-4-yn-1-ol
5-(TRIMETHYLSILYL)-4-PENTYN-1-OL
5-(triMethylsilyl)pent-4-yn-1-ol
4-Pentyn-1-ol, 5-(trimethylsilyl)-
CAS 13224-84-5
InChI InChI=1/C8H16OSi/c1-10(2,3)8-6-4-5-7-9/h9H,4-5,7H2,1-3H3

13224-84-5 - Physico-chemical Properties

Molecular FormulaC8H16OSi
Molar Mass156.3
Density0.861 g/mL at 25 °C
Boling Point76 °C/15 mmHg (lit.)
Flash Point184°F
Vapor Presure0.154mmHg at 25°C
Specific Gravity0.852
pKa14.97±0.10(Predicted)
Storage ConditionSealed in dry,2-8°C
Refractive Indexn 20/D 1.457

13224-84-5 - Risk and Safety

Risk Codes10 - Flammable
Safety Description16 - Keep away from sources of ignition.
UN IDs1987
WGK Germany3
HS Code29310099

13224-84-5 - Introduction

5-(Trimethylsilyl)-4-pentyn-1-ol, also known as TMSC ⋅ C≡ C⋅ CH2 ⋅ OH, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
1. appearance: colorless liquid.
2. molecular formula: C9H18OSi.
3. Molecular weight: 174.32g/mol.
4. Melting point:-70°C.
5. Boiling point: 64-65°C.
6. density: 0.801g/cm³.
7. Solubility: Soluble in organic solvents, such as ether, tetrahydrofuran and dimethylformamide.

Use:
1. TMSC • C ≡ C • CH2 • OH can be used as an important reagent in organic synthesis, can participate in the synthesis of sawcarbazole, and has potential medical and biological applications.
2. It can be used as a reagent in cross-coupling reactions to construct carbon-carbon bonds.
3. Due to its very active nucleophilic-acceptor properties, TMSC ⋅ C≡ C≡CH2-OH can also be used to synthesize various organic compounds.

Preparation Method:
The preparation of TMSC ⋅ C≡ C⋅ CH2 ⋅ OH can be achieved by a variety of methods. A common preparation method is the reaction of trimethyl (pentynyl) silane and methanol in the presence of cerium (IV) chloroformate.

Safety Information:
1. TMSC • C≡ C • CH2 • OH should be careful to prevent contact with oxygen during storage or use, because it may burn in the air.
2. Avoid prolonged exposure to high temperatures and fire sources to prevent explosions.
3. Use should wear appropriate protective gloves and goggles, and operate in a well-ventilated environment.
4. When using and handling, care should be taken to avoid skin and eye contact to avoid irritation and damage.
5. Keep away from flammable and explosive substances during storage and handling.

Please note that TMSC ⋅ C≡ C⋅ CH2 ⋅ OH is a chemical reagent and must be operated under suitable laboratory conditions by professionals with laboratory safety knowledge and experience.
Last Update:2024-04-09 21:04:16
13224-84-5
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
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SHANGHAI ACMEC BIOCHEMICAL TECHNOLOGY CO., LTD.
Spot supply
Product Name: 5-Trimethylsilyl-4-prntyn-1-ol Visit Supplier Webpage Request for quotation
CAS: 13224-84-5
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
WhatsApp: +86-18621343501
Shanghai Macklin Biochemical Co., Ltd
Spot supply
Product Name: 5-Trimethylsilyl-4-prntyn-1-ol Visit Supplier Webpage Request for quotation
CAS: 13224-84-5
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328 Click to send a QQ message
WhatsApp: +86-18821248368
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