129931-46-0
3-Chloro-2-fluoro-5-(trifluoromethyl)benzamide
CAS: 129931-46-0
Molecular Formula: C8H4ClF4NO
129931-46-0 - Names and Identifiers
129931-46-0 - Physico-chemical Properties
| Molecular Formula | C8H4ClF4NO |
| Molar Mass | 241.57 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD01631399 |
129931-46-0 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
129931-46-0 - Introduction
3-Chloro-2-fluoro-5-(trifluoromethyl)benzamide is an organic compound whose chemical formula is C8H4ClF4N.
Nature:
-Appearance: Colorless solid
-melting point: 105-108 ℃
-Boiling point: 284-286 ℃
-Solubility: Insoluble in water, soluble in organic solvents such as dimethyl sulfoxide and dichloromethane
Use:
-As a drug intermediate: 3-Chloro-2-fluoro-5-(trifluoromethyl)benzamide is an intermediate for the synthesis of certain drugs.
-For research: This compound is used in organic synthesis and medicinal chemistry research.
Preparation Method:
3-Chloro-2-fluoro-5-(trifluoromethyl)benzamide can be prepared by the following steps:
1.3-Chloro -2-fluoro -5-nitrobenzamide is reacted with a trifluoromethane-based compound
2. After a series of reactions and treatments, 3-Chloro-2-fluoro-5-(trifluoromethyl)benzamide products were obtained.
Safety Information:
- 3-Chloro-2-fluoro-5-(trifluoromethyl)benzamide is irritating and may be harmful to the skin and eyes.
-Wear protective gloves, goggles and protective clothing during operation.
-Avoid inhaling its powder or contact with skin and eyes.
-For accidental contact, rinse immediately with plenty of water and seek medical treatment.
Nature:
-Appearance: Colorless solid
-melting point: 105-108 ℃
-Boiling point: 284-286 ℃
-Solubility: Insoluble in water, soluble in organic solvents such as dimethyl sulfoxide and dichloromethane
Use:
-As a drug intermediate: 3-Chloro-2-fluoro-5-(trifluoromethyl)benzamide is an intermediate for the synthesis of certain drugs.
-For research: This compound is used in organic synthesis and medicinal chemistry research.
Preparation Method:
3-Chloro-2-fluoro-5-(trifluoromethyl)benzamide can be prepared by the following steps:
1.3-Chloro -2-fluoro -5-nitrobenzamide is reacted with a trifluoromethane-based compound
2. After a series of reactions and treatments, 3-Chloro-2-fluoro-5-(trifluoromethyl)benzamide products were obtained.
Safety Information:
- 3-Chloro-2-fluoro-5-(trifluoromethyl)benzamide is irritating and may be harmful to the skin and eyes.
-Wear protective gloves, goggles and protective clothing during operation.
-Avoid inhaling its powder or contact with skin and eyes.
-For accidental contact, rinse immediately with plenty of water and seek medical treatment.
Last Update：2024-04-09 02:00:56
