129385-59-7

129385-59-7 - Names and Identifiers

Name	trans-11-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz-[2,3:6,7]-oxepino-[4,5-c]-pyrrol-1-one
Synonyms	Asenapine pharMaceutical interMediate
CAS	129385-59-7

129385-59-7 - Physico-chemical Properties

Molecular Formula	C17H14ClNO2
Molar Mass	299.75
Density	1.311
Boling Point	428.4±45.0 °C(Predicted)
pKa	-0.70±0.20(Predicted)
Storage Condition	Sealed in dry,Store in freezer, under -20°C

129385-59-7 - Introduction

Trans-( |-)-11-chloro-2, 3,3a,12b-tetrahydro-2-methyl-1H-dibenzo [2,3:6,7] oxazolo [4,5-c] pyrrol-1-one is an organic compound with the chemical formula C21H17ClNO and a molecular weight of 335.82g/mole.

properties: trans-( |-)-11-chloro -2,3,3a,12b-tetrahydro -2-methyl -1H-dibenzo [2,3:6,7] oxatrizo [4,5-c] pyrrole -1-one common properties are as follows:
-Appearance: White crystal or crystalline powder.
-Melting point: about 159-160°C.
-Solubility: Soluble in organic solvents (such as chloroform, dimethyl sulfoxide), insoluble in water.

use: trans-( |-)-11-chloro-2, 3,3a,12b-tetrahydro -2-methyl -1H-dibenzo [2,3:6,7] oxazolo [4,5-c] pyrrole -1-one is a pharmaceutical intermediate. Due to its unique structure and biological activity, the compound can be used in the field of medicine, for the synthesis of anti-cancer drugs and other drugs.

preparation method: the preparation method of trans-( |-)-11-chloro -2,3,3a,12b-tetrahydro -2-methyl -1H-dibenzo [2,3:6,7] oxazolo [4,5-c] pyrrole -1-one is relatively complicated and usually requires multi-step reactions. One of the common preparation methods is through chemical synthesis, first synthesis of intermediates, followed by chlorination reaction, to obtain the final product.

Safety information: When using trans-( |-)-11-chloro-2, 3,3a,12b-tetrahydro -2-methyl -1H-dibenzo [2,3:6,7] oxazeand [4,5-c] pyrrol-1-one, it is necessary to observe the relevant safety procedures. Since this compound is an organic chloride, it may have harmful properties to the human body and the environment, so the following should be noted:
-Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water.
-During the operation, good ventilation conditions should be maintained to avoid inhalation of dust or gas from the compound.
-During storage and handling, avoid contact with oxidants or strong acids to prevent dangerous reactions.
-When handling the compound, take appropriate personal protective measures, such as wearing protective gloves, goggles and protective clothing.

Please note that the above information is for reference only, specific nature, use, preparation and safety information, but also need to consult the chemical literature and professional information to obtain more detailed and accurate information.

Last Update：2024-04-09 21:04:16