Name | 7-(2'-Deoxyadenosin-N6-yl)aristolactam I |
Synonyms | A-Aai Aristolactam A 7-(deoxyadenosin-N(6)-yl)aristolactam I 7-(2'-Deoxyadenosin-N6-yl)aristolactam I Adenosine, 2'-deoxy-N-(5,6-dihydro-8-methoxy-5-oxobenzo[f]-1,3-benzodioxolo[6,5,4-cd]indol-7-yl)- |
CAS | 127191-86-0 |
Molecular Formula | C27H22N6O7 |
Molar Mass | 542.5 |
Density | 1.87±0.1 g/cm3 (20 ºC 760 Torr) |
Appearance | Lens. |
Storage Condition | 2-8℃ |
Physical and Chemical Properties | Density: 1.87g/cm3; Refractive index: 1.89 |
chemical properties | density: 1.87g/cm3; Refractive index: 1.89 |
use | reference substance for identification, standard substance for content determination, active monomer |
application | aristolochic lactam a, a highly active compound, can be seen to generate aristolochic lactam after oxidation, and its toxic nitro group provides binding sites for binding dna bases. Because it has strong electrophilic ability, it can bind electrophilic to the extracyclic amino group of dna base to generate corresponding adduct products, mutating ras gene and p53 gene |