1227465-61-3 - Names and Identifiers
Name | 5-(1-Aminoethyl)-1,3,4-thiadiazol-2-amine dihydrochloride
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Synonyms | 1,3,4-Thiadiazole-2-methanamine, 5-amino-α-methyl- 5-(1-Aminoethyl)-1,3,4-thiadiazol-2-amine dihydrochloride 1-(5-Imino-4,5-dihydro-1,3,4-thiadiazol-2-yl)ethan-1-amine
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CAS | 1227465-61-3
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1227465-61-3 - Physico-chemical Properties
Molecular Formula | C4H8N4S
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Molar Mass | 144.2 |
Storage Condition | Room Temprature |
Sensitive | IRRITANT |
MDL | MFCD16039370 |
1227465-61-3 - Risk and Safety
1227465-61-3 - Introduction
5-(1-Aminoethyl)-1,3,4-thiadiazol-2-amine dihydrochloride, also known as 5-(1-aminoethyl)-1,3,4-thiadiazol-2-amine dihydrochloride, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White Crystal
-Formula: C5H13N5S · 2HCl
-Molecular weight: 255.13g/mol
-melting point: 252-254 ℃
-Solubility: Soluble in water, slightly soluble in ethanol and ether.
Use:
- 5-(1-Aminoethyl)-1,3,4-thiadiazol-2-amine dihydrochloride is widely used in the pharmaceutical field as a drug intermediate.
-It can be used to synthesize anti-epileptic and anti-cancer drugs, such as tiotropium and chronic myeloid leukemia treatment drugs.
Preparation Method:
- 5-(1-Aminoethyl)-1,3,4-thiadiazol-2-amine dihydrochloride can be obtained by reacting 5-chloro-1, 3,4-thiadiazol-2-amine with 1-aminoethylamine.
-Specific preparation method: First, 5-chloro-1, 3,4-thiadiazol -2-amine is reacted with aminoethylamine in ethanol to obtain the target compound. Then, the target product was prepared as a dihydrochloride salt by adding hydrochloric acid.
Safety Information:
The safety of -5-(1-Aminoethyl)-1,3,4-thiadiazol-2-amine dihydrochloride requires a detailed toxicity assessment of the compound.
-When using or handling the compound, follow laboratory safety practices and wear appropriate personal protective equipment.
-Avoid direct contact with skin and eyes, and maintain a well-ventilated working environment.
-If inhaled or ingested, seek medical help immediately and bring the compound's safety data sheet for medical reference.
Last Update:2024-04-09 21:01:54