1220021-15-7 - Names and Identifiers
1220021-15-7 - Physico-chemical Properties
Molecular Formula | C14H20ClNO2
|
Molar Mass | 269.77 |
Storage Condition | Room Temprature |
Sensitive | IRRITANT |
MDL | MFCD13559846 |
1220021-15-7 - Risk and Safety
1220021-15-7 - Introduction
2-(4-Piperidinyl) ethylbenzoic acid hydrochloride (2-(4-Piperidinyl)ethyl benzoate hydrochloride) is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystalline powder
-Molecular formula: C15H20ClNO2
-Molecular Weight: 289.78
-Melting point: 160-162°C
-Solubility: Soluble in water and alcohol, slightly soluble in ether, ketone and other organic solvents
Use:
- 2-(4-Piperidinyl) ethyl benzoic acid hydrochloride is commonly used as a chemical reagent
-For the reaction of amine protecting group (N-protection) and ester group (C-protection) in organic synthesis
-In drug synthesis, it can be used as an intermediate for anesthetics, antidepressants, anxiolytics, etc.
Preparation Method:
The preparation method of 2-(4-Piperidinyl) ethyl benzoic acid hydrochloride can be carried out by the following steps:
1. benzoic acid and 4-oxo -2-fluorobenzoyl chloride were reacted to obtain 2-amino benzoic acid
2.2.2-Aminobenzoic acid reacts with 4-piperazine ethanol under alkaline conditions to obtain 2-(4-Piperidinyl) ethyl benzoate
3. reacting the above product with hydrochloric acid to obtain 2-(4-Piperidinyl) ethyl benzoic acid hydrochloride
Safety Information:
- 2-(4-Piperidinyl) ethyl benzoic acid hydrochloride has low toxicity, but it is still necessary to comply with laboratory safety practices, such as wearing appropriate personal protective equipment (such as laboratory gloves and protective glasses).
-Avoid direct contact with the mouth, eyes and skin. If contact occurs, rinse immediately with water.
-When storing and handling, it should be stored in a closed container and kept away from fire or high temperature.
Last Update:2024-04-09 02:00:57