1218791-45-7 - Names and Identifiers
Name | N,N-Diethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine
|
Synonyms | 2-DiethylaMinopyriMidine-5-boronic acid, pinacol ester N,N-Diethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine 2-Pyrimidinamine, N,N-diethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
|
CAS | 1218791-45-7
|
1218791-45-7 - Physico-chemical Properties
Molecular Formula | C14H24BN3O2
|
Molar Mass | 277.17 |
Storage Condition | 2-8°C |
Sensitive | Irritant |
MDL | MFCD12546555 |
1218791-45-7 - Introduction
N,N-Diethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine is an organic compound with the chemical formula C16H26BNO2 and the following properties and uses:
Nature:
-Appearance: N,N-Diethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine is a colorless to yellow liquid.
-Solubility: It can be dissolved in some common organic solvents, such as chloroform, dimethyl sulfoxide and methanol.
-Stability: It is relatively stable at room temperature, but may decompose under high temperature, strong acid or strong alkali conditions.
Use:
-Functional group: Its 1,3, 2-dioxaborane ring can be used to synthesize functional groups in other compounds, such as esters, amides and ketones.
-Ligand: It can be used as a ligand in organic synthesis and participate in metal-catalyzed reactions, such as Suzuki coupling reaction, Heck reaction and Morse-Simson reaction.
Preparation Method:
The synthesis of N,N-Diethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine generally involves the following steps:
1.1,3, 2-dioxaborane ring was prepared by synthetic reaction.
2. The 1,3, 2-dioxaborane ring is reacted with 5-chloro-2-aminopyridine to obtain the target compound.
Safety Information:
- N,N-Diethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-amine has limited safety data, so appropriate protective measures need to be taken when using and handling.
-It may be irritating to the eyes, skin and mucous membranes, so direct contact should be avoided.
-When using, please refer to the relevant safety data sheets and operating instructions, and strictly follow the laboratory's safety regulations.
Last Update:2024-04-10 22:29:15