R-(-)-Manidipine-d4 (R-(-)-Manidipine-d4) is a deuterium-labeled R-(-)-Manidipine with the following properties:
1. Properties: R-(-)-Manidipine-d4 is a solid, white crystalline powder, with good thermal stability. Its chemical formula is C35H40D4N4O6 and its molecular weight is 608.71g/mol.
2. Use: R-(-)-Manidipine-d4 is mainly used in the study of drug metabolism and drug analysis. As an internal standard for pharmacokinetic studies, it can be used to determine the pharmacokinetic parameters of R-(-)-Manidipine and to understand the metabolism of drugs in vivo.
3. Preparation method: The preparation of R-(-)-Manidipine-d4 usually adopts the method of synthetic chemistry. This method can be used to label deuterium by introducing a deuterated reagent during the synthesis of R-(-)-Manidipine, making it R-(-)-Manidipine-d4.
4. Safety information: for R-(-)-Manidipine-d4 safety information, due to the lack of relevant research and data, there is no clear safety assessment results. However, as a labeling reagent for drug metabolism research, it should be used in accordance with laboratory safety practices. Avoid inhalation, ingestion or contact with skin during operation, and wear appropriate personal protective equipment when necessary. If discomfort or accident occurs, immediately consult a professional for help.