1217442-62-0 - Names and Identifiers
Name | 4-Methoxy-13C,d3-estradiol
|
Synonyms | 4-Methoxy-13C,d3-estradiol (8R,9S,13S,14S,17S)-4-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 4-Hydroxyestradiol 4-methyl-13C,d3 ether, 4-Methoxy-13C,d3-estradiol, 1,3,5(10)-Estratriene-2,3,17-triol 4-methyl-13C,d3 ether, 3,4,17β-Trihydroxy-1,3,5(10)-estratriene 4-methyl-13C,d3 ether, 3,17β-Dihydroxy-4-methoxy-13C,d3-1,3,5(10)-estratriene
|
CAS | 1217442-62-0
|
1217442-62-0 - Physico-chemical Properties
Molecular Formula | C19H26O3
|
Molar Mass | 303.41694 |
Storage Condition | -20°C |
1217442-62-0 - Risk and Safety
Risk Codes | R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
R50 - Very Toxic to aquatic organisms
|
Safety Description | S22 - Do not breathe dust.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
|
UN IDs | UN 2811 6.1/PG 1 |
1217442-62-0 - Introduction
4-Methoxy-13C,d3-estradiol is a marker compound, also known as a metabolite marker. It has the property that the hydrogen atoms in the estradiol molecule are replaced by 13C and deuterium (d3), and upon methoxylation an oxidized 13C-d3 metabolite is formed.
This compound is commonly used in biological metabolism studies, especially in pharmacokinetic and pharmacokinetic studies. It can be used as a marker substance, by tracking and quantitative analysis of its metabolites in vivo, so as to understand the transformation process and distribution of drugs in vivo.
To prepare 4-Methoxy-13C, the d3-estradiol method is usually through synthetic chemical methods, and the use of specific stable isotope labeling reagents to introduce 13C and deuterium. The specific synthetic route may vary depending on the purpose of the study and the experimental conditions.
Regarding safety information, this compound may be toxic to the human body, so it is necessary to use appropriate protective measures during operation, such as wearing gloves and masks, and operate in a well-ventilated laboratory. For detailed information on toxicity and hazards, reference should be made to the relevant safety data sheets. If you are unfamiliar or unsure of the risks when using, consult a chemical laboratory professional.
Last Update:2024-04-09 20:49:11