1216815-21-2 - Names and Identifiers
1216815-21-2 - Physico-chemical Properties
Molecular Formula | C14H24BrNO3
|
Molar Mass | 334.25 |
Storage Condition | Room Temprature |
Sensitive | IRRITANT |
MDL | MFCD11840293 |
1216815-21-2 - Introduction
8-Boc-3-bromomethyl-2-oxazole-8-azaspiro [4.5] decane, also known as BOC-EDAC, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White solid
-Melting point: about 100-104°C
-Molecular formula: C14H18BrN3O2
-Molecular weight: 345.22g/mol
-Solubility: Soluble in most organic solvents, such as dimethylformamide, dichloromethane, etc.
Use:
- BOC-EDAC are mainly used as intermediates and catalysts for organic synthesis reactions.
-It has important applications in the synthesis of peptides or drugs, especially in the activation and coupling reactions in peptide synthesis.
-It can also be used to synthesize other compounds, such as Boc-protected amides.
Preparation Method:
-The preparation of BOC-EDAC is usually carried out by the following steps:
1. First, Boc-protected amides is reacted with 3-bromomethyl-2-oxazole to generate 3-Boc-bromomethyl-2-oxazole.
2. Then, 3-Boc-bromomethyl-2-oxazole is reacted with dimethylformamide isocyanate (DIAD) under basic conditions to obtain 8-Boc-3-bromomethyl-2-oxazole-8-azaspiro [4.5] decane.
Safety Information:
- BOC-EDAC have low toxicity under normal laboratory conditions.
-Avoid contact with skin and eyes during operation, and wear protective gloves and goggles when necessary.
-Follow relevant safety practices and chemical management principles during use and storage.
-When disposing of waste, follow local regulations.
Last Update:2024-04-09 21:01:54