5-HYDROXY OMEPRAZOLE-D3 (5-hydroxyomeprazole D3) is a deuterated 5-hydroxyomeprazole compound. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-chemical formula: C17H13D3N3O3S
-Molecular weight: 347.46g/mol
-Appearance: White or off-white crystalline powder
-Melting Point: about 155-157 ℃
-Solubility: Poor solubility in water, and better solubility in organic solvents such as methanol and dimethyl sulfoxide.
Use:
5-HYDROXY OMEPRAZOLE-D3 are mainly used as marker compounds in drug development. Labeled compounds are often used in pharmacokinetic studies, drug metabolism studies, drug interaction studies and other fields. The addition of 5-hydroxyomeprazole D3 can assist in the study of the pharmacokinetic properties and metabolic pathways of omeprazole drugs.
Method:
The synthesis of the 5-HYDROXY OMEPRAZOLE-D3 is usually obtained by a deuteration reaction method. The specific step is to first react omeprazole with a deuterating reagent, and then obtain 5-hydroxyomeprazole-D3 through appropriate isolation and purification steps.
Safety Information:
- 5-HYDROXY OMEPRAZOLE-D3 There are currently no relevant toxicity data, but it is generally considered to be less toxic.
-Safety measures are required during handling and handling, such as wearing personal protective equipment, avoiding inhalation of dust, and avoiding contact with skin and eyes.
-Follow the relevant safety operating procedures when using it, and dispose of it according to laboratory regulations. Before any laboratory operation, it is recommended to consult the safety data sheet of the compound or consult a professional.