1214358-19-6 - Names and Identifiers
1214358-19-6 - Physico-chemical Properties
Molecular Formula | C8H4F6
|
Molar Mass | 214.11 |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD14698654 |
1214358-19-6 - Risk and Safety
1214358-19-6 - Introduction
2-(Difluoromethyl)-4-fluoro-1-(trifluoromethyl)benzene, also known as 2-(difluoromethyl)-4-fluoro-1-(trifluoromethyl)benzene, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 2-(Difluoromethyl)-4-fluoro-1-(trifluoromethyl)benzene are colorless to pale yellow crystals.
-Solubility: It is soluble in common organic solvents such as ethanol, toluene and acetone. Its solubility in water is low.
-Melting point and boiling point: The melting point is about 60-62°C, and the boiling point is about 150-152°C.
-Molecular formula: C9H3F7
Use:
- 2-(Difluoromethyl)-4-fluoro-1-(trifluoromethyl)benzene is an important organic synthesis intermediate, which is commonly used in drug synthesis, material science and pesticide research.
-It can also be used as a reaction reagent to participate in different organic synthesis reactions.
Preparation Method:
The preparation method of 2-(Difluoromethyl)-4-fluoro-1-(trifluoromethyl)benzene can be carried out by the following steps:
1. Alkali promotion:
(CF3)2CHX (X = Cl, Br) C6H4F-CO2-Et → (CF3)2CH-C6H4F
2. nucleophilic substitution:
(CF3)2CH-C6H4F B (OH)2 → (CF3)2CH-C6H4F-B(OH)2
3. Hydrogenation reduction:
(CF3)2CH-C6H4F-B(OH) 2H2, Pd/C→ 2-(Difluoromethyl)-4-fluoro-1-(trifluoromethyl)benzene
Safety Information:
2-(Difluoromethyl)-4-fluoro-1-(trifluoromethyl)benzene has limited safety information, so be careful when using or handling:
-It may be irritating and corrosive to the eyes, skin and respiratory tract.
-Wear appropriate protective equipment such as gloves, glasses and respiratory protection when using.
-should be operated in a well-ventilated environment.
-It should be kept away from high temperatures, open flames and oxidants.
-Please read and follow the chemical safety instructions carefully, and follow the correct laboratory operating procedures.
Last Update:2024-04-09 20:49:11