(4-bromo-3-fluorophenyl)methanamine hydrochloride is an organic compound with the chemical formula C7H7BrFN · HCl. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline solid
-Molecular weight: 225.49g/mol
-melting point: 165-168 ℃
-Solubility: Slightly soluble in water, soluble in some organic solvents such as methanol and ethanol
Use:
- (4-bromo-3-fluorophenyl)methanamine hydrochloride can be used as intermediates in organic synthesis, and are often used in the preparation of drugs and pesticides.
-It can also be used as a chemical reagent for research and laboratory analysis.
Preparation Method:
(4-bromo-3-fluorophenyl) The preparation method of methanamine hydrochloride can be carried out by the following steps:
1.4-bromo -3-fluoronitrobenzene and thionamide are reacted to generate 4-bromo -3-fluoroaniline.
2.4-bromo -3-fluoroaniline reacts with chloromethane to generate 4-bromo -3-fluorobenzylamine.
3. Finally, 4-bromo-3-fluorobenzylamine is reacted with hydrochloric acid to generate (4-bromo-3-fluorophenyl)methanamine hydrochloride.
Safety Information:
- (4-bromo-3-fluorophenyl)methanamine hydrochloride may be irritating to the eyes, skin and respiratory system, please avoid contact.
-When using, please wear appropriate personal protective equipment, such as gloves and safety glasses.
-When storing, it should be stored in a dry and ventilated place to avoid contact with oxidants and strong acids.
-It is recommended to use in a suitable laboratory environment and follow safe operating procedures. If accidentally contact or inhalation, please timely medical treatment.