1211584-18-7

1211584-18-7 - Names and Identifiers

Name	1H-Pyrazolo[3,4-b]pyridin-3-aMine, 5-broMo-6-Methyl-
Synonyms	5-BroMo-6-Methyl-1H-pyrazolo[3,4-b]pyridin-3-aMine 1H-Pyrazolo[3,4-b]pyridin-3-aMine, 5-broMo-6-Methyl- L-1363 5-Bromo-6-methyl-2H-pyrazolo[3,4-b]pyridin-3-amine
CAS	1211584-18-7

1211584-18-7 - Physico-chemical Properties

Molecular Formula	C7H7BrN4
Molar Mass	227.06
Density	1.845±0.06 g/cm3(Predicted)
Boling Point	412.8±40.0 °C(Predicted)
pKa	10.02±0.40(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature

1211584-18-7 - Introduction

1H-Pyrazolo [3,4-b] pyridine-3-amino-5-bromo-6-methyl is an organic compound with the chemical formula C10H8BrN3. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 1H-pyrazolo [3,4-b] pyridine-3-amino-5-bromo-6-methyl is a white crystal or crystalline powder.
-Solubility: It is soluble in common organic solvents such as ethanol, dimethyl sulfoxide and dichloromethane, but difficult to dissolve in water.
-Melting point: Its melting point is about 130-132°C.

Use:
-Research compound: 1H-pyrazolo [3,4-b] pyridine-3-amino-5-bromo-6-methyl is often used in organic synthesis reactions as an important intermediate. It can be used to synthesize a variety of compounds containing pyrazole, pyridine or bipyrazole ring, such as drugs, dyes, functional materials, etc.
-Drug development: Compounds with pyrazole and pyridine structures usually have certain biological activities, so 1H-pyrazolo [3,4-b] pyridine-3-amino-5-bromo-6-methyl can be Used to synthesize potential drug candidate compounds.

Preparation Method:
The preparation of 1H-pyrazolo [3,4-b] pyridine-3-amino-5-bromo-6-methyl can be carried out by a variety of methods, one of which involves the following steps:
1. First, sodium nitrite is used to oxidize bromobenzene to generate 1-bromo -4-nitrobenzene.
2.1-bromo -4-nitrobenzene is reacted with methyl carbamate to generate methyl 4-nitrophenyl formyl formate.
3. the reaction of methyl 4-nitrophenyl formate with 1,3-propanediamine to generate methyl 1,3-propanediamine phenyl formate.
4. Finally, reduction and amination of methyl 1,3-propanediamine phenyl formate were carried out to obtain 1H-pyrazolo [3,4-b] pyridine -3-amino -5-bromo -6-methyl.

Safety Information:
-1H-Pyrazolo [3,4-b] pyridine-3-amino-5-bromo-6-methyl may be toxic to humans and good laboratory practices need to be followed.
-Wear appropriate personal protective equipment such as lab gloves, goggles and lab coats during use.
-Avoid contact with incompatible substances such as oxidants and strong acids during storage and handling.
-The compound should be stored in a dry, cool place, and away from fire and heat sources.
-For further safety information, such as first aid and treatment, please review the compound's safety data sheet or consult a professional.

Last Update：2024-04-09 20:02:46