1190319-59-5

1190319-59-5 - Names and Identifiers

Name	1H-Pyrrolo[2,3-c]pyridine-4-carbonitrile
Synonyms	4-Cyano-6-azaindole 6-Azaindole-4-carbonitrile 1H-pyrrolo[2,3-c]pyridine-4-carbonitrile 1H-Pyrrolo[2,3-c]pyridine-4-carbonitrile
CAS	1190319-59-5

1190319-59-5 - Physico-chemical Properties

Molecular Formula	C8H5N3
Molar Mass	143.15
Density	1.33
Boling Point	380℃
Flash Point	129℃
Storage Condition	2-8°C
Sensitive	IRRITANT
MDL	MFCD12963363

1190319-59-5 - Risk and Safety

Hazard Class

IRRITANT

1190319-59-5 - Introduction

1H-Pyrrolo[2,3-c]pyridine-4-carbonitrile is an organic compound with the chemical formula C9H5N3. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance: 1H-Pyrrolo[2,3-c]pyridine-4-carbonitrile is a white to slightly yellow crystalline or powdery solid.
-Melting point: Its melting point range is about 188-190°C.
-Solubility: Soluble in some organic solvents (such as methanol, dichloromethane).

Use:
- 1H-Pyrrolo[2,3-c]pyridine-4-carbonitrile has a wide range of applications in the field of drug development. It can be used as a drug intermediate for the synthesis of various bioactive molecules, such as anti-tumor drugs, antibacterial drugs and so on.

Preparation Method:
- 1H-Pyrrolo[2,3-c]pyridine-4-carbonitrile has many preparation methods, and the common ones are as follows:
1. It is synthesized from pyrrolo [2,3-c] pyridine-4-methanol through dehydration and demethylation.
2. From pyrrolo [2,3-c] pyridine-4-methanol, pyrrolo [2,3-c] pyridine-4-acid is obtained by acylation reaction, and then 1H-Pyrrolo[2,3-c]pyridine-4-carbonitrile is obtained by cyanation reaction.
3. can also be achieved through other different synthesis path.

Safety Information:
- 1H-Pyrrolo[2,3-c]pyridine-4-carbonitrile specific safety information may vary depending on national regulations. Generally speaking, it is a low-toxic compound, but the following items still need to be paid attention:
-use should wear protective glasses and gloves, avoid contact with the skin and inhalation of dust.
-Avoid contact with oxidants, strong acids and other substances.
-Operate in a well-ventilated place and keep it properly.
-In case of contact or misuse, seek medical attention immediately.

Last Update：2024-04-09 19:06:02