117391-48-7 - Names and Identifiers
117391-48-7 - Physico-chemical Properties
Molecular Formula | C9H10BrNO2
|
Molar Mass | 244.09 |
Density | 1.585±0.06 g/cm3(Predicted) |
Melting Point | 221-223°C |
Boling Point | 366.8±32.0 °C(Predicted) |
pKa | 3.62±0.10(Predicted) |
Storage Condition | Room Temprature |
117391-48-7 - Risk and Safety
117391-48-7 - Introduction
3-Amino-3-(2-bromo-phenyl)-propionic acid is an organic compound with the chemical formula C9H9BrNO2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White crystalline powder.
-Solubility: Soluble in water and organic solvents, such as alcohols, ethers and ketones.
-Melting point: about 138-142°C.
Use:
3-Amino-3-(2-bromo-phenyl)-propionic acid is mainly used as an intermediate in organic synthesis, for the synthesis of other organic compounds or drugs. It can also be used to design and synthesize biologically active molecules.
Preparation Method:
3-Amino-3-(2-bromo-phenyl)-propionic acid can be synthesized by the following steps:
1. First, 2-bromobenzaldehyde and dibutyl malonate are subjected to a Knoevenagel condensation reaction to obtain butyl 2-bromophenylmalonate.
2. Then, butyl 2-bromophenylmalonate is reacted with ammonia water and heated under alkaline conditions to generate 3-Amino-3-(2-bromo-phenyl)-propionic acid.
3. Finally, the pure product was obtained through the steps of crystallization, filtration and drying.
Safety Information:
3-Amino-3-(2-bromo-phenyl)-propionic acid has limited specific toxicity data, but the following safety precautions should be noted during use:
-Avoid contact with skin, eyes and respiratory tract. Use should wear protective gloves, glasses and masks.
-Operate in a well-ventilated area.
-Store in a cool, dry and sealed container, away from fire and oxidizing agents.
In general, personnel handling the compound in chemical laboratories or industrial production environments should follow appropriate safe operating procedures and use and handle the compound correctly in accordance with relevant regulations and standards.
Last Update:2024-04-09 21:32:44