115104-28-4
(E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT
CAS: 115104-28-4
Molecular Formula: C26H27ClN2O3S2
115104-28-4 - Names and Identifiers
115104-28-4 - Physico-chemical Properties
| Molecular Formula | C26H27ClN2O3S2 |
| Molar Mass | 515.09 |
| Density | 1.327±0.06 g/cm3(Predicted) |
| Melting Point | 65-70°C |
| Boling Point | 712.3±60.0 °C(Predicted) |
| Solubility | Soluble in DMSO (up to 50 mg/ml). |
| Appearance | Off-white solid. |
| Color | Yellow |
| pKa | 4.27±0.10(Predicted) |
| Storage Condition | Store at -20°C |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months. |
| In vitro study | L-660,711(MK-571) inhibited the binding of [3H]LTD4 in guinea pig lung with a Ki value of 0.22±0.15 nM (n = 35), and inhibited the binding of [3H]LTD4 in human lung, the Ki value was 2.1±1.8 nM (n = 29). L660,711 had low or no activity against [3H]LTC4, and the IC50 in guinea pig lung was 23±11 μm (n = 16), the IC50 in human lung was 32 μm (n = 1). |
| In vivo study | MK-571 was well tolerated by healthy young adults. After oral administration, MK-571 is rapidly absorbed. The plasma concentration reached a peak after 1.1-1.5 hours after administration. |
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Product Name: (E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT Visit Supplier Webpage Request for quotation
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View History
115104-28-4
2,5-dichloro-N-(4-methylbenzo[d]thiazol-2-yl)benzamide
2-{4-[(3,4-dichlorobenzyl)oxy]-3-ethoxyphenyl}-3-(4-ethylphenyl)-2,3-dihydro-4(1H)-quinazolinone
1,4-Benzodioxin-6-carboxamide, N-[3-(5-chloro-2-benzoxazolyl)phenyl]-2,3-dihydro-
3,8''-Biapigenin
2H-Naphtho[2,3-a]quinolizine-6,8,13(1H)-trione, 7-acetyl-3,4-dihydro- (9CI)
4-Fluoro-alpha-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)styrene
N-{4-amino-6-[(3,5-dimethyl-1-piperidinyl)methyl]-1,3,5-triazin-2-yl}-N-(4-ethoxyphenyl)amine
(4S)-2-(((R)-2-aMino-2-(4-hydroxyphenyl)acetaMido)Methyl)-5,5-diMethylthiazolidine-4-carboxylic acid
1-(3-Chloro-2-propenyl)-4-methoxybenzene
2,5-dichloro-N-(4-methylbenzo[d]thiazol-2-yl)benzamide
2-{4-[(3,4-dichlorobenzyl)oxy]-3-ethoxyphenyl}-3-(4-ethylphenyl)-2,3-dihydro-4(1H)-quinazolinone
1,4-Benzodioxin-6-carboxamide, N-[3-(5-chloro-2-benzoxazolyl)phenyl]-2,3-dihydro-
3,8''-Biapigenin
2H-Naphtho[2,3-a]quinolizine-6,8,13(1H)-trione, 7-acetyl-3,4-dihydro- (9CI)
4-Fluoro-alpha-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)styrene
N-{4-amino-6-[(3,5-dimethyl-1-piperidinyl)methyl]-1,3,5-triazin-2-yl}-N-(4-ethoxyphenyl)amine
(4S)-2-(((R)-2-aMino-2-(4-hydroxyphenyl)acetaMido)Methyl)-5,5-diMethylthiazolidine-4-carboxylic acid
1-(3-Chloro-2-propenyl)-4-methoxybenzene