1150163-97-5
Ethyl 5-amino-1-(2-bromophenyl)-4-cyano-1H-pyrazole-3-carboxylate
CAS: 1150163-97-5
Molecular Formula: C13H11BrN4O2
1150163-97-5 - Names and Identifiers
1150163-97-5 - Physico-chemical Properties
| Molecular Formula | C13H11BrN4O2 |
| Molar Mass | 335.16 |
| Storage Condition | 2-8°C |
| Sensitive | IRRITANT |
| MDL | MFCD09835742 |
1150163-97-5 - Introduction
Ethyl 5-amino -1-(2-bromophenyl)-4-cyano-1H-pyrazole-3-carboxylic acid ethyl ester is an organic compound. Its chemical formula is C13H11BrN4O2. The following is a description of some of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Ethyl 5-amino -1-(2-bromophenyl)-4-cyano-1H-pyrazole-3-carboxylic acid ethyl ester is a brown-yellow or yellow solid.
-Melting point: about 136-138 ℃.
-Solubility: Ethyl 5-amino -1-(2-bromophenyl)-4-cyano-1H-pyrazole-3-carboxylic acid ethyl ester is soluble in some organic solvents, such as dimethyl sulfoxide, Dichloromethane and ethanol.
Use:
Ethyl 5-amino -1-(2-bromophenyl)-4-cyano-1H-pyrazole-3-carboxylic acid ethyl ester can be used in organic synthesis reactions, such as the synthesis of metal organic compounds, catalytic reactions and the preparation of fluorescent materials.
Preparation Method:
Ethyl 5-amino -1-(2-bromophenyl)-4-cyano-1H-pyrazole-3-carboxylic acid ethyl ester can be prepared through a series of reaction steps. A common synthetic method is to first react 2-bromobenzoic acid with p-propyl carbamate to yield N-(2-bromobenzyl)-p-propyl carbamate. N-(2-Bromobenzyl)-p-propylcarbamate is then reacted with sodium cyanide under basic conditions to give 5-amino -1-(2-bromophenyl)-4-cyano-1H-pyrazole. Finally, 5-amino -1-(2-bromophenyl)-4-cyano-1H-pyrazole is reacted with glycolation by esterification to give ethyl 5-amino -1-(2-bromophenyl)-4-cyano-1H-pyrazole-3-carboxylate.
Safety Information:
-Ethyl 5-amino -1-(2-bromophenyl)-4-cyano-1H-pyrazole-3-carboxylic acid ethyl ester is a chemical that needs to be used under safe operating conditions.
-During operation, avoid contact with skin and eyes. Immediately after contact, rinse with plenty of water.
-During operation, good ventilation should be maintained to avoid inhalation of its vapor or dust.
-should be away from fire and high temperature environment, stored in a sealed container, avoid exposure.
-When using and storing, please observe the relevant safety procedures, and use personal protective equipment, such as gloves, protective glasses and laboratory coats.
Nature:
-Appearance: Ethyl 5-amino -1-(2-bromophenyl)-4-cyano-1H-pyrazole-3-carboxylic acid ethyl ester is a brown-yellow or yellow solid.
-Melting point: about 136-138 ℃.
-Solubility: Ethyl 5-amino -1-(2-bromophenyl)-4-cyano-1H-pyrazole-3-carboxylic acid ethyl ester is soluble in some organic solvents, such as dimethyl sulfoxide, Dichloromethane and ethanol.
Use:
Ethyl 5-amino -1-(2-bromophenyl)-4-cyano-1H-pyrazole-3-carboxylic acid ethyl ester can be used in organic synthesis reactions, such as the synthesis of metal organic compounds, catalytic reactions and the preparation of fluorescent materials.
Preparation Method:
Ethyl 5-amino -1-(2-bromophenyl)-4-cyano-1H-pyrazole-3-carboxylic acid ethyl ester can be prepared through a series of reaction steps. A common synthetic method is to first react 2-bromobenzoic acid with p-propyl carbamate to yield N-(2-bromobenzyl)-p-propyl carbamate. N-(2-Bromobenzyl)-p-propylcarbamate is then reacted with sodium cyanide under basic conditions to give 5-amino -1-(2-bromophenyl)-4-cyano-1H-pyrazole. Finally, 5-amino -1-(2-bromophenyl)-4-cyano-1H-pyrazole is reacted with glycolation by esterification to give ethyl 5-amino -1-(2-bromophenyl)-4-cyano-1H-pyrazole-3-carboxylate.
Safety Information:
-Ethyl 5-amino -1-(2-bromophenyl)-4-cyano-1H-pyrazole-3-carboxylic acid ethyl ester is a chemical that needs to be used under safe operating conditions.
-During operation, avoid contact with skin and eyes. Immediately after contact, rinse with plenty of water.
-During operation, good ventilation should be maintained to avoid inhalation of its vapor or dust.
-should be away from fire and high temperature environment, stored in a sealed container, avoid exposure.
-When using and storing, please observe the relevant safety procedures, and use personal protective equipment, such as gloves, protective glasses and laboratory coats.
Last Update：2024-04-10 22:29:15
