1072946-64-5

1072946-64-5 - Names and Identifiers

Name	(5-Cyano-2-(trifluoromethoxy)phenyl)boronic acid
Synonyms	5-Cyano-2-(trifluoromethoxy)phenylboronic acid (5-Cyano-2-(trifluoromethoxy)phenyl)boronic acid Boronic acid, B-[5-cyano-2-(trifluoromethoxy)phenyl]-
CAS	1072946-64-5

1072946-64-5 - Physico-chemical Properties

Molecular Formula	C8H5BF3NO3
Molar Mass	230.94
Appearance	Solid
Storage Condition	2-8°C
Sensitive	IRRITANT
MDL	MFCD11053857

1072946-64-5 - Introduction

(5-Cyano-2-(trifluoromethoxy)phenyl)boronic is an organoboron compound with the chemical formula C8H5BF3NO3.

Nature:
-Appearance: White crystalline powder
-Melting point: 170-172°C
-Solubility: Soluble in some organic solvents such as ammonia, ethanol, dimethyl ketone and chloroform, slightly soluble in water

Use:
-As an important intermediate in organic synthesis, it can be used to synthesize a variety of drugs, pesticides and chemicals.
-Can be used as a phenylboronic acid reagent, which can undergo a Suzuki reaction with halogenated aromatic hydrocarbons to construct C- C bonds.
-Used as a light-emitting layer material in the synthesis of organic electroluminescent devices (OLED).

Preparation Method:
(5-Cyano-2-(trifluoromethoxy)phenyl)boronic acid can be prepared:
-5-cyano-2-iodobenzene is reacted with trifluoromethyl alcohol to obtain 5-cyano-2-(trifluoromethoxy) benzene.
-The obtained compound is reacted with a salt of boric acid and hydrolyzed to obtain the target product.

Safety Information:
- (5-Cyano-2-(trifluoromethoxy)phenyl)boronic acid is relatively safe, but still need to pay attention to the following matters:
-Keep away from fire and high temperature.
-In the operation and handling, should wear protective gloves and glasses, maintain good ventilation.
-In case of contact with skin or eyes, rinse immediately with plenty of water.
-During storage and use, keep away from inflammables and dangerous goods such as acids, alkalis and oxidants.

Last Update：2024-04-09 02:00:57