1-羟基-3H-1Λ3,2-苯并碘杂噁戊环-3-酮

1-羟基-3H-1Λ3,2-苯并碘杂噁戊环-3-酮 - Names and Identifiers

Name	1-hydroxy-1lambda~3~,2-benziodoxol-3(1H)-one
Synonyms	1-Hydroxy-1,2-benziodoxole-3-one 1,2-Benziodoxol-3(1H)-one,1-hydroxy- 1-hydroxy-3H-1λ3,2-benziodaoxol-3-one 1-Hydroxy-1-ioda(III)-2-oxaindan-3-one 1-Hydroxy-2-oxa-1-ioda(III)indan-3-one 1-Hydroxy-2-Oxa-1-Ioda(Iii)Indan-3-One 1-hydroxy-1lambda~3~,2-benziodoxol-3(1H)-one 1-Hydroxy-1,3-dihydro-1,2-benziodoxole-3-one 1-Hydroxy-3-oxo-1,3-dihydro-1,2-benzoiodoxole
CAS	131-62-4
InChI	InChI=1/C7H5IO3/c9-7-5-3-1-2-4-6(5)8(10)11-7/h1-4,10H

1-羟基-3H-1Λ3,2-苯并碘杂噁戊环-3-酮 - Physico-chemical Properties

Molecular Formula	C7H5IO3
Molar Mass	264.017
Melting Point	260 °C (decomp)(Solv: water (7732-18-5))
pKa	8.12±0.20(Predicted)
Storage Condition	2-8℃

1-羟基-3H-1Λ3,2-苯并碘杂噁戊环-3-酮 - Upstream Downstream Industry

Raw Materials

2-Iodobenzoic acid

1-羟基-3H-1Λ3,2-苯并碘杂噁戊环-3-酮 - Introduction

1-Hydroxy-2-oxa-1-iodo (III) hydrochlorin-3-one, also known as HIOK(Hydroxyoxabenzotriazole Ketone), is an organic compound. The following is an introduction to some of its properties, uses, methods and safety information:

Nature:
-Appearance: HIOK is a white crystalline powder.
-Melting point: Its melting point is between 200-201°C.
-Solubility: HIOK is soluble in alcohol and ester solvents, but has low solubility in water.

Use:
- HIOK is often used as an active esterifying agent and acylating agent in organic synthesis, and can be used to synthesize compounds with important biological activities.
-It can also be used as an intermediate for the synthesis of polypeptides, nucleotides and other biologically active molecules.
- HIOK is widely used in drug discovery and synthetic chemistry.

Preparation Method:
- HIOK can be prepared by 2-fluoro-1-iodo-4-hydroxybenzene (as raw material) through a series of reaction steps such as oxidation, ring shrinkage, and dehydration.

Safety Information:
- HIOK is irritating to the skin, eyes and respiratory tract in solid and powder form, so care should be taken to avoid contact during operation.
-Wear appropriate protective equipment such as gloves, goggles and masks when used.
-Please operate in a well-ventilated laboratory environment to avoid inhaling its dust.
-When storing and handling HIOK, appropriate hazardous waste disposal regulations should be followed to ensure safety and environmental protection.

Last Update：2024-04-09 20:49:11