1-(TERT-BUTYLOXYCARBONYL-AMINO)-3,6-DIOXA-8-OCTANEAMINE
Boc-1-amino-3,6-dioxa-8-octanediamine
CAS: 153086-78-3
Molecular Formula: C11H24N2O4
1-(TERT-BUTYLOXYCARBONYL-AMINO)-3,6-DIOXA-8-OCTANEAMINE - Names and Identifiers
1-(TERT-BUTYLOXYCARBONYL-AMINO)-3,6-DIOXA-8-OCTANEAMINE - Physico-chemical Properties
| Molecular Formula | C11H24N2O4 |
| Molar Mass | 248.32 |
| Density | 1.046 g/mL at 20 °C |
| Boling Point | 365.2±27.0 °C(Predicted) |
| pKa | 12.23±0.46(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.4570 to 1.4610 |
| MDL | MFCD03788155 |
| Use | Uses for the preparation of numerous linking tags, polymerization monomers and ionophore, etc., such as biotinylation reagents. |
1-(TERT-BUTYLOXYCARBONYL-AMINO)-3,6-DIOXA-8-OCTANEAMINE - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
| UN IDs | 2735 |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-21 |
| HS Code | 29241990 |
| Hazard Class | 8 |
| Packing Group | Ⅲ |
1-(TERT-BUTYLOXYCARBONYL-AMINO)-3,6-DIOXA-8-OCTANEAMINE - Upstream Downstream Industry
1-(TERT-BUTYLOXYCARBONYL-AMINO)-3,6-DIOXA-8-OCTANEAMINE - Introduction
tert-Butyl 2-(2-(2-aminoethoxy) ethoxy) ethylcarbamate (Boc-NH-PEG3) is an organic compound. Its molecular formula is C14H29NO6, and its structure contains two ethoxy groups and one aminoethoxy group. The following is a description of the nature, use, preparation and safety information of the Boc-NH-PEG3:
Nature:
-Appearance: colorless or yellowish transparent liquid
-Solubility: Soluble in water and common organic solvents
-Melting point: about 25-30°C
-Molecular weight: about 315.39g/mol
Use:
Boc-NH-PEG3 are commonly used in the biomedical field, mainly for the following purposes:
-Modification of proteins and polypeptides: It can be used to synthesize polypeptides and protein compounds with specific functions and solubility.
-Drug delivery: As a drug carrier, it plays an important role in the drug delivery system.
-Biomaterials: Preparation of biocompatible and biodegradable materials, such as hydrogels, nanoparticles, etc.
Preparation Method:
The preparation method of Boc-NH-PEG3 is more complicated and is generally divided into multi-step reactions. The specific method is different, the following is a common method:
1. Using 1-amino-2-(tert-butoxycarbonyl)ethoxy-2-ethanol as raw material, it reacts with 1,3-dichloropropane to generate 2,5,8,11-tetrachlorotridecane.
2.2,5,8,11-tetrachlorotridecane is reacted with triethanolamine to generate 2-(2-(2-aminoethoxy) ethoxy) ethanol.
3.2-(2-(2-aminoethoxy) ethoxy) ethanol reacts with N,N'-bis (2-propionyloxyethyl) tetramine to generate the target product Boc-NH-PEG3.
Safety Information:
- Boc-NH-PEG3 are general organic compounds, and you need to pay attention to safe operation when using them. Contact with skin, eyes and inhalation should be avoided.
-Wear protective gloves, goggles and dust mask during operation.
-storage should be placed in a dry, cool place, away from fire and oxidant.
-use process to be careful to prevent its leakage, so as not to cause pollution to the environment.
-Do not mix with strong oxidants and strong acids to avoid dangerous reactions.
Please note that the above information is for reference only. Please refer to relevant literature and chemical safety information for specific operation and use.
Nature:
-Appearance: colorless or yellowish transparent liquid
-Solubility: Soluble in water and common organic solvents
-Melting point: about 25-30°C
-Molecular weight: about 315.39g/mol
Use:
Boc-NH-PEG3 are commonly used in the biomedical field, mainly for the following purposes:
-Modification of proteins and polypeptides: It can be used to synthesize polypeptides and protein compounds with specific functions and solubility.
-Drug delivery: As a drug carrier, it plays an important role in the drug delivery system.
-Biomaterials: Preparation of biocompatible and biodegradable materials, such as hydrogels, nanoparticles, etc.
Preparation Method:
The preparation method of Boc-NH-PEG3 is more complicated and is generally divided into multi-step reactions. The specific method is different, the following is a common method:
1. Using 1-amino-2-(tert-butoxycarbonyl)ethoxy-2-ethanol as raw material, it reacts with 1,3-dichloropropane to generate 2,5,8,11-tetrachlorotridecane.
2.2,5,8,11-tetrachlorotridecane is reacted with triethanolamine to generate 2-(2-(2-aminoethoxy) ethoxy) ethanol.
3.2-(2-(2-aminoethoxy) ethoxy) ethanol reacts with N,N'-bis (2-propionyloxyethyl) tetramine to generate the target product Boc-NH-PEG3.
Safety Information:
- Boc-NH-PEG3 are general organic compounds, and you need to pay attention to safe operation when using them. Contact with skin, eyes and inhalation should be avoided.
-Wear protective gloves, goggles and dust mask during operation.
-storage should be placed in a dry, cool place, away from fire and oxidant.
-use process to be careful to prevent its leakage, so as not to cause pollution to the environment.
-Do not mix with strong oxidants and strong acids to avoid dangerous reactions.
Please note that the above information is for reference only. Please refer to relevant literature and chemical safety information for specific operation and use.
Last Update：2024-04-09 19:05:53
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View History
1-(TERT-BUTYLOXYCARBONYL-AMINO)-3,6-DIOXA-8-OCTANEAMINE
2-(4-硝基苯基)-1-十八烷基-1H-苯并咪唑-5-磺酸
3-(PENTAFLUOROPHENYL)PROPYLDIMETHYLCHLOROSILANE
(2-氯-吡啶-3-基)-哌嗪-1-基-甲酮盐酸盐
磷酸化凝胶配制试剂盒(固定浓度) 6%
1-[(1-ethyl-5-methyl-1H-pyrazol-4-yl)methyl]-3,5-dimethyl-1H-pyrazol-4-amine
copper-binding peptide
2,5-Pyrrolidinedione, 1-[3-[2-[2-[2-[2-[(2,4-dinitrophenyl)amino]ethoxy]ethoxy]ethoxy]ethoxy]-1-oxopropoxy]- (9CI)
2-氯-3-甲基-3,5-二氢-4H-吡咯并[3,2-d]嘧啶-4-酮
N-OCTYLDIISOPROPYL DIMETHYL AMINO SILANE
2-(4-硝基苯基)-1-十八烷基-1H-苯并咪唑-5-磺酸
3-(PENTAFLUOROPHENYL)PROPYLDIMETHYLCHLOROSILANE
(2-氯-吡啶-3-基)-哌嗪-1-基-甲酮盐酸盐
磷酸化凝胶配制试剂盒(固定浓度) 6%
1-[(1-ethyl-5-methyl-1H-pyrazol-4-yl)methyl]-3,5-dimethyl-1H-pyrazol-4-amine
copper-binding peptide
2,5-Pyrrolidinedione, 1-[3-[2-[2-[2-[2-[(2,4-dinitrophenyl)amino]ethoxy]ethoxy]ethoxy]ethoxy]-1-oxopropoxy]- (9CI)
2-氯-3-甲基-3,5-二氢-4H-吡咯并[3,2-d]嘧啶-4-酮
N-OCTYLDIISOPROPYL DIMETHYL AMINO SILANE
Raw Materials for 1-(TERT-BUTYLOXYCARBONYL-AMINO)-3,6-DIOXA-8-OCTANEAMINE
Acetamide, N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-2,2,2-trifluoro-
Boc-NH-PEG2-NH-Boc
1,8-Diazido-3,5-dioxaoctane
t-Boc-N-Amido-PEG2-Azide
Carbonochloridic acid, 1,1-diMethylethyl ester
Boc-NH-PEG2-NH-Boc
1,8-Diazido-3,5-dioxaoctane
t-Boc-N-Amido-PEG2-Azide
Carbonochloridic acid, 1,1-diMethylethyl ester
Downstream Products for 1-(TERT-BUTYLOXYCARBONYL-AMINO)-3,6-DIOXA-8-OCTANEAMINE