1-(TERT-BUTOXYCARBONYL)1H-1,2,4-TRIAZOLE - Names and Identifiers
Name | 1-(tert-butoxycarbonyl)1H-1,2,4-triazole
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Synonyms | 1-BOC-1,2,4-TRIAZOLE LABOTEST-BB LT00771764 Butoxycarbonyltriazole 1-BOC-1H-1,2,4-TRIAZOLE 1-T-boc-1H-1,2,4-triazole 1-Tert-Butoxycarbonyl-1,2,4-Triazole 1-TERT-BUTOXYCARBONYL-1,2,4-TRIAZOLE 1-(tert-butoxycarbonyl)1H-1,2,4-triazole 1-(TERT-BUTOXYCARBONYL)1H-1,2,4-TRIAZOLE 1-tert-butyl 1H-1,2,4-triazole-1-carboxylate
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CAS | 41864-24-8
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EINECS | 255-570-5 |
InChI | InChI=1/C7H11N3O2/c1-7(2,3)12-6(11)10-5-8-4-9-10/h4-5H,1-3H3 |
1-(TERT-BUTOXYCARBONYL)1H-1,2,4-TRIAZOLE - Physico-chemical Properties
Molecular Formula | C7H11N3O2
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Molar Mass | 169.18 |
Density | 1.17g/cm3 |
Melting Point | 43-47°C |
Boling Point | 75°C0.35mm Hg(lit.) |
Flash Point | 111°C |
Vapor Presure | 0.0126mmHg at 25°C |
Appearance | powder to crystal |
Color | White to Almost white |
Storage Condition | Inert atmosphere,2-8°C |
Refractive Index | 1.533 |
MDL | MFCD00042665 |
1-(TERT-BUTOXYCARBONYL)1H-1,2,4-TRIAZOLE - Risk and Safety
Safety Description | S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
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WGK Germany | 3 |
FLUKA BRAND F CODES | 10-21 |
HS Code | 29339900 |
1-(TERT-BUTOXYCARBONYL)1H-1,2,4-TRIAZOLE - Introduction
1-(tert-butoxycarbonyl)1H-1,2,4-triazole is a chemical compound with the formula C9H13N3O2. The following is a description of some of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless crystalline solid.
-Melting point: about 125-130°C.
-Solubility: Soluble in some organic solvents, such as dichloromethane and dimethylformamide.
-Stability: relatively stable under normal conditions.
Use:
- 1-(tert-butoxycarbonyl)1H-1,2,4-triazole can be used as a chemical reagent for the synthesis of other compounds.
-In organic synthesis, it is often used as a protecting group to protect amino or carboxyl groups to prevent unwanted reactions.
Preparation Method:
- 1-(tert-butoxycarbonyl)1H-1,2,4-triazole can be prepared by the following steps:
1. through the reaction of trichloroformic acid and tert-butyl magnesium oxide to obtain tert-butyl oxide trichloroformate.
2. The tert-butyl oxide trichloroformate is reacted with 1,2,4-triazole to obtain 1-(tert-butoxycarbonyl)1H-1,2,4-triazole product.
Safety Information:
- 1-(tert-butoxycarbonyl)1H-1,2,4-triazole has higher safety and lower toxicity.
-During handling and storage, appropriate protective measures should be taken to avoid contact with skin, eyes and respiratory system.
-Use the process should maintain good ventilation.
-When handling this compound, follow safe operating procedures to avoid harmful substances or accidents.
Last Update:2024-04-10 22:29:15