1-(CYCLOBUTYLCARBONYL)-4-PIPERIDINONE - Names and Identifiers
1-(CYCLOBUTYLCARBONYL)-4-PIPERIDINONE - Physico-chemical Properties
Molecular Formula | C10H15NO2
|
Molar Mass | 181.23 |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD09951084 |
1-(CYCLOBUTYLCARBONYL)-4-PIPERIDINONE - Risk and Safety
1-(CYCLOBUTYLCARBONYL)-4-PIPERIDINONE - Introduction
1-(Cyclobutylcarbonyl)piperidin-4-one is an organic compound, the chemical formula is C11H17NO2, the structure contains cyclobutane and piperidine groups.
In terms of properties, the compound is a colorless to light yellow solid with a special odor. It is soluble in alcohols, ketones and ether at room temperature, insoluble in water. Its melting point is 60-64 degrees Celsius.
The compound has a wide range of uses in organic synthesis. It can be used as a pharmaceutical intermediate for the synthesis of anti-cancer drugs, antidepressants and sedatives. In addition, it can also be used to synthesize pesticides, spices and dyes.
preparation method, we can through the following steps to synthesize 1-(Cyclobutylcarbonyl)piperidin-4-one. First, piperidine and bromocyclobutane are reacted to produce 1-(bromocyclobutyl) piperidine. The 1-(bromocyclobutyl) piperidine is then reacted with sodium acetate to give 1-(cyclobutanyl) piperidine. Finally, 1-(cyclobutanyl) piperidine is reacted with carbon dioxide for carbonylation to give the final product 1-(Cyclobutylcarbonyl)piperidin-4-one.
In terms of safety information, the compound has a low risk of toxicity under normal use. However, proper laboratory safety measures, such as wearing protective glasses and gloves, are still required during handling and storage. In addition, prolonged exposure to the skin and inhalation of gases should be avoided. If contact with the compound, should immediately rinse with water, and timely medical treatment.
Last Update:2024-04-10 22:30:50