1-(4-Aminophenyl)piperidine
4-(1-Piperidino)aniline
CAS: 2359-60-6
Molecular Formula: C11H16N2
1-(4-Aminophenyl)piperidine - Names and Identifiers
| Name | 4-(1-Piperidino)aniline |
| Synonyms | TIMTEC-BB SBB010087 4-Piperidinoaniline 4-PIPERIDINOANILINE 4-PIPERIDIN-1-YLANILINE 4-(1-Piperidino)aniline 4-(piperidin-1-yl)aniline N-(4-aminophenyl)piperidine 1-(4-Aminophenyl)piperidine N-(4-AMINOPHENYL)PIPERIDINE 1-(p-Aminophenyl)piperidine 4-(1-PIPERIDINO)ANILINE [1-(4-AMINOPHENYL)PIPERIDINE] |
| CAS | 2359-60-6 |
| InChI | InChI=1/C11H16N2/c12-10-4-6-11(7-5-10)13-8-2-1-3-9-13/h4-7H,1-3,8-9,12H2 |
1-(4-Aminophenyl)piperidine - Physico-chemical Properties
| Molecular Formula | C11H16N2 |
| Molar Mass | 176.26 |
| Density | 1.074±0.06 g/cm3(Predicted) |
| Melting Point | 26-29°C(lit.) |
| Boling Point | 140-142°C 1mm |
| Flash Point | >230°F |
| Vapor Presure | 6.32E-05mmHg at 25°C |
| BRN | 139525 |
| pKa | 7.79±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | n20/D 1.5937(lit.) |
| MDL | MFCD00051688 |
1-(4-Aminophenyl)piperidine - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R36/37 - Irritating to eyes and respiratory system. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S22 - Do not breathe dust. |
| UN IDs | 2811 |
| WGK Germany | 3 |
| HS Code | 29333990 |
| Hazard Note | Harmful |
| Hazard Class | 6.1 |
| Packing Group | III |
1-(4-Aminophenyl)piperidine - Introduction
4-(1-Piperidino)aniline is an organic compound with the chemical formula C11H16N2. Its main properties are as follows:
1. Appearance: 4-(1-Piperidino)aniline is a colorless to light yellow crystalline solid.
2. Solubility: It is soluble in most organic solvents, such as acetone, methanol and ethanol, but its solubility in water is low.
3. Saturated vapor pressure: It has a lower saturated vapor pressure.
4. Stability: 4-(1-Piperidino)aniline is stable at room temperature, but may decompose at high temperature.
5. Ph value: its solution is weakly alkaline, pH value is about 8-9.
4-(1-Piperidino)aniline is mainly used as follows:
1. Organic synthesis: It can be used as an intermediate in organic synthesis and used to synthesize other biologically active compounds.
2. Drug research: Due to its activity in biological systems, 4-(1-Piperidino)aniline is also used in drug research and development.
3. Dye manufacturing: It can be used for the synthesis and production of dyes.
The method for preparing 4-(1-Piperidino)aniline mainly includes the following steps:
1. Reacting aniline with 1-piperidinecarboxaldehyde to generate 4-(1-piperidinyl) benzaldehyde.
2.4-(1-piperidinyl) benzaldehyde is reduced to give 4-(1-Piperidino)aniline.
Regarding safety information, you need to pay attention to the following points:
1. 4-(1-Piperidino)aniline may be irritating to the skin, eyes and mucous membranes. Pay attention to safety precautions when using it, such as wearing gloves and goggles.
2. Avoid inhalation or ingestion, avoid contact with exposed skin and eyes.
3. During use or storage, keep away from fire or high temperature environment to avoid fire and explosion hazards.
4. Refer to the chemical's safety data sheet (SDS) for detailed safety information before use.
1. Appearance: 4-(1-Piperidino)aniline is a colorless to light yellow crystalline solid.
2. Solubility: It is soluble in most organic solvents, such as acetone, methanol and ethanol, but its solubility in water is low.
3. Saturated vapor pressure: It has a lower saturated vapor pressure.
4. Stability: 4-(1-Piperidino)aniline is stable at room temperature, but may decompose at high temperature.
5. Ph value: its solution is weakly alkaline, pH value is about 8-9.
4-(1-Piperidino)aniline is mainly used as follows:
1. Organic synthesis: It can be used as an intermediate in organic synthesis and used to synthesize other biologically active compounds.
2. Drug research: Due to its activity in biological systems, 4-(1-Piperidino)aniline is also used in drug research and development.
3. Dye manufacturing: It can be used for the synthesis and production of dyes.
The method for preparing 4-(1-Piperidino)aniline mainly includes the following steps:
1. Reacting aniline with 1-piperidinecarboxaldehyde to generate 4-(1-piperidinyl) benzaldehyde.
2.4-(1-piperidinyl) benzaldehyde is reduced to give 4-(1-Piperidino)aniline.
Regarding safety information, you need to pay attention to the following points:
1. 4-(1-Piperidino)aniline may be irritating to the skin, eyes and mucous membranes. Pay attention to safety precautions when using it, such as wearing gloves and goggles.
2. Avoid inhalation or ingestion, avoid contact with exposed skin and eyes.
3. During use or storage, keep away from fire or high temperature environment to avoid fire and explosion hazards.
4. Refer to the chemical's safety data sheet (SDS) for detailed safety information before use.
Last Update：2024-04-09 21:21:28
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View History
1-(4-Aminophenyl)piperidine
oxophenarsine hydrochloride
碘化铷
Acetylaminofluorenone, 2-
4-羟基-7-甲氧基喹啉-6-甲酰胺
Benzenesulfonamide, N-[1-[(acetyloxy)methyl]decyl]-4-methyl-
1-Pentanol, 5-[(tetrahydro-2H-pyran-2-yl)oxy]-, 1-acetate
1-Imidazolidineacetic acid, 2,5-dioxo-4,4-dipropyl-
Ethanesulfonic acid, 2-((2,3-dimercaptopropyl)thio)-, sodium salt
potassium [2-[[[5-[(2-chloro-5-sulphophenyl)azo]-2-hydroxyphenyl]methylene]amino]benzoato(3-)]hydroxychromate(1-)
oxophenarsine hydrochloride
碘化铷
Acetylaminofluorenone, 2-
4-羟基-7-甲氧基喹啉-6-甲酰胺
Benzenesulfonamide, N-[1-[(acetyloxy)methyl]decyl]-4-methyl-
1-Pentanol, 5-[(tetrahydro-2H-pyran-2-yl)oxy]-, 1-acetate
1-Imidazolidineacetic acid, 2,5-dioxo-4,4-dipropyl-
Ethanesulfonic acid, 2-((2,3-dimercaptopropyl)thio)-, sodium salt
potassium [2-[[[5-[(2-chloro-5-sulphophenyl)azo]-2-hydroxyphenyl]methylene]amino]benzoato(3-)]hydroxychromate(1-)