1-(3-二甲基氨基丙基)-3-乙基碳二亚胺
N-(3-dimethylaminopropyl)-N'-ethyl-carbodiimide
CAS: 1892-57-5
Molecular Formula: C8H17N3
1-(3-二甲基氨基丙基)-3-乙基碳二亚胺 - Names and Identifiers
| Name | N-(3-dimethylaminopropyl)-N'-ethyl-carbodiimide |
| Synonyms | WSCI WSCD WATER-SOLUBLE CARBODIIMIDE [3-(Dimethylamino)propyl]ethylcarbodiimide 1-(3-dimethylaminopropyl)-N-ethylcarbodiimide 1-(3-DIMETHYLAMINOPROPYL)-3-ETHYLCARBODIIMIDE 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide 1-ETHYL-3-(3-DIMETHYLAMINOPROPYL) CARBODIIMIDE N-(3-DIMETHYLAMINOPROPYL)-N'-ETHYLCARBODIIMIDE N-ETHYL-N'-(3-DIMETHYLAMINOPROPYL)CARBODIIMIDE N-(3-dimethylaminopropyl)-N'-ethyl-carbodiimide |
| CAS | 1892-57-5 |
| EINECS | 217-579-2 |
| InChI | InChI=1/C8H17N3/c1-4-9-8-10-6-5-7-11(2)3/h4-7H2,1-3H3 |
| InChIKey | LMDZBCPBFSXMTL-UHFFFAOYSA-N |
1-(3-二甲基氨基丙基)-3-乙基碳二亚胺 - Physico-chemical Properties
| Molecular Formula | C8H17N3 |
| Molar Mass | 155.24 |
| Density | 0.877 g/mL at 20 °C (lit.) |
| Melting Point | 115℃ |
| Boling Point | 66-68°C/1mm |
| Flash Point | 66-68°C/1mm |
| Water Solubility | Soluble in water. |
| Solubility | Chloroform |
| Vapor Presure | 0.373mmHg at 25°C |
| Appearance | Clear Liquid |
| Specific Gravity | 0.885 |
| Color | Colorless to slightly yellow |
| BRN | 507429 |
| pKa | 9.52±0.28(Predicted) |
| Storage Condition | -20°C |
| Sensitive | Air Sensitive |
| Refractive Index | n20/D 1.461 |
| MDL | MFCD00044916 |
1-(3-二甲基氨基丙基)-3-乙基碳二亚胺 - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | 34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2735 8/PG 3 |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 1-3-10 |
| TSCA | Yes |
| HS Code | 29252900 |
| Hazard Class | 8 |
| Packing Group | III |
1-(3-二甲基氨基丙基)-3-乙基碳二亚胺 - Reference
| Reference Show more | 1. Jiao Yanhua, Liang Yuanyuan, Guo Weiqiang. Research on HCG chemiluminescence immunoassay based on magnetic microspheres [J]. Journal of Hangzhou Normal University (Natural Science Edition), 2014, 000(005):495-498. 2. Liu Hong, Mao Xiang, Shuang Liu Huan, et al. Preparation of PEG Modified Fe_3O_4 Nanoparticles (MNPs) and Study on Catalytic Oxidation of VB_1 [J]. Journal of Tianjin Agricultural University 2018. 3. He, B., Du, G. Novel electrochemical aptasensor for ultrasensitive detection of sulfadimidine based on covalently linked multi-walled carbon nanotubes and in situ synthesized gold nanoparticle composites. Anal Bioanal Chem 410, 2901-2910 (2018). https:// do 4. Li, Xiangyu, et al. "Folate receptor-targeting mesoporous silica-coated gold nanorod nanoparticles for the synergistic photothermal therapy and chemotherapy of rheumatoid arthritis." RSC Advances 11.6 (2021): 3567-3574.https:// doi.org/10.1039/D0RA08689D 5. [IF = 4.316] Dan Cheng et al. "An Electrochemical DNA Sensing Platform Using Carboxyl Functionalized Graphene as the Electrode Modified Material." J Electrochem Soc. 2017 Apr;164(6): h345 6. [IF = 2.896] Bao-Shan He et al. "Electrochemical aptasensor based on aptamer-complimentary strand conjugate and thionine for sensitive detection of tetracycline with multi-walled carbon nanotubes and gold nanoparticles amplification." Anal Methods-Uk. 2018 Feb;10(7):783 7. [IF = 11.161] Ye Lili et al. "Dendrimer-modified gold nanorods as a platform for combinational gene therapy and photothermal therapy of tumors." J Exp Clin Canc Res. 2021 Dec;40(1):1-16 8. [IF = 5.03] Delu Zhao et al. "Effect of altering photocrosslinking conditions on the physical properties of alginate gels and the survival of photoencapsulated cells." Polym Degrad Stabil. 2020 Sep;179:109297 9. [IF = 3.361] Xiangyu Li et al. "Folate receptor-targeting mesoporous silica-coated gold nanorod nanoparticles for the synergistic photothermal therapy and chemotherapy of rheumatoid arthritis." Rsc Adv. 2021 Jan;11(6): 3567-3574 |
1-(3-二甲基氨基丙基)-3-乙基碳二亚胺 - Reference Information
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| introduction | 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide is a condensing agent, colorless or light yellow liquid, commonly used as its hydrochloride. |
| Use | 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, referred to as EDC hydrochloride, is a water-soluble peptide coupling agent and a general carbonyl activation reagent. It can be used to bond amides with secondary amines, react with phosphate groups, cross-link proteins with nucleic acids, and prepare such as immune crosslinks, used for carbonyl modification in proteins, etc. |
Last Update：2024-09-24 08:52:44
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View History
1-(3-二甲基氨基丙基)-3-乙基碳二亚胺
N-(4-乙酰氨基苯基)-3-羟基萘-2-甲酰胺
反式-4-氨基环乙醇盐酸盐 (暂无)
2-(6-(环戊氧基)吡啶-3-基)乙-1-胺二盐酸盐
3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester)
N-(4-乙酰氨基苯基)-3-羟基萘-2-甲酰胺
反式-4-氨基环乙醇盐酸盐 (暂无)
2-(6-(环戊氧基)吡啶-3-基)乙-1-胺二盐酸盐
3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester)