1-(2,4-dihydroxy-5-nitrophenyl)ethanone - Names and Identifiers
1-(2,4-dihydroxy-5-nitrophenyl)ethanone - Physico-chemical Properties
Molecular Formula | C8H7NO5
|
Molar Mass | 197.14 |
Density | 1.52g/cm3 |
Melting Point | 142-146°C(lit.) |
Boling Point | 347.9°C at 760 mmHg |
Flash Point | 155.8°C |
Vapor Presure | 2.59E-05mmHg at 25°C |
Refractive Index | 1.637 |
1-(2,4-dihydroxy-5-nitrophenyl)ethanone - Risk and Safety
Hazard Symbols | T - Toxic
|
Risk Codes | R25 - Toxic if swallowed
R36 - Irritating to the eyes
R43 - May cause sensitization by skin contact
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37 - Wear suitable protective clothing and gloves.
|
UN IDs | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
1-(2,4-dihydroxy-5-nitrophenyl)ethanone - Introduction
1-(2,) ethanone is an organic compound with the chemical formula C8H7NO4. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 1-(2, 9001) ethanone is a yellow crystal or crystalline powder.
-Melting point: about 175-180 degrees Celsius.
-Solubility: Soluble in alcohol and ketone, almost insoluble in water.
-Stability: Stable, but there will be color changes under light.
Use:
-Pharmaceutical field: 1-(2, 1) ethanone can be used as an intermediate for the preparation of certain drugs.
-Analytical Chemistry: Can be used as a reagent for organic synthesis and analytical chemistry.
Method:
The synthesis method of 1-(2,) ethanone can be obtained by the reaction of p-nitrophenol and bromoethanone. Specific steps include:
1. Dissolve nitrophenol and sodium carbonate in alkaline solution.
2. Slowly add bromoethyl ketone to keep the reaction system alkaline.
3. Stir the reaction at room temperature for several hours.
4. The product was obtained by filtration and purified by water washing and crystallization to obtain the target product.
Safety Information:
- 1-(2,) ethanone is less harmful to the human body and the environment under normal operating conditions. But still need to pay attention to the following safety measures:
-Contact with eyes, skin or inhalation of dust may cause irritation and direct contact should be avoided.
-Appropriate personal protective equipment, such as lab gloves, goggles and protective masks, should be worn during laboratory operations.
-During the operation, care should be taken to avoid dust and avoid inhaling its odor.
-Waste should be disposed of properly in accordance with local regulations.
-Avoid direct sunlight during use or storage to prevent the color of the product from changing.
Last Update:2024-04-09 02:00:45